ZNF653 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000161914 T095013_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables AF-2 domain binding activity and transcription corepressor activity. Involved in extracellular negative regulation of signal transduction and negative regulation of nucleic acid-templated transcription. Predicted to be located in extracellular region. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF653
M08248_2.00		 Homo sapiens
NWTTHNYDHCYKCCGACWNHWAWD
HWTWDNWGTCGGMRGDHRNDAAWN		 ChIP-seq
Najafabadi et al.(2015b)
ZNF653		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000293771 C2H2 ZF 467 492
ENSP00000293771 C2H2 ZF 498 522
ENSP00000293771 C2H2 ZF 528 550
ENSP00000293771 C2H2 ZF 556 578
ENSP00000293771 C2H2 ZF 586 609
ENSP00000465166 C2H2 ZF 4 29
ENSP00000465166 C2H2 ZF 35 59
ENSP00000465166 C2H2 ZF 65 82
ENSP00000467069 C2H2 ZF 79 104
ENSP00000467069 C2H2 ZF 110 134
ENSP00000467069 C2H2 ZF 140 162

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

39 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Zfp653 Mus musculus ENSMUSG00000038895 I 0.827
ZNF653 Macaca mulatta ENSMMUG00000020617 I 0.827
ZNF653 Loxodonta africana ENSLAFG00000026889 I 0.827
ENSPANG00000016446 Papio anubis ENSPANG00000016446 I 0.827
ENSPPYG00000009584 Pongo abelii ENSPPYG00000009584 I 0.827
Zfp653 Rattus norvegicus ENSRNOG00000014065 I 0.827
ZNF653 Pan troglodytes ENSPTRG00000010507 I 0.827
ZNF653 Echinops telfairi ENSETEG00000007616 I 0.827
ENSNLEG00000012591 Nomascus leucogenys ENSNLEG00000012591 I 0.827
ENSCSAG00000006753 Chlorocebus sabaeus ENSCSAG00000006753 I 0.827
ZNF653 Callithrix jacchus ENSCJAG00000005551 I 0.827
ZNF653 Pteropus vampyrus ENSPVAG00000014895 I 0.825
ZNF653 Bos taurus ENSBTAG00000014415 I 0.825
Myotis_brandtii_Znf653_10003855 Myotis brandtii Myotis_brandtii_Znf653_10003855 I 0.825
ZNF653 Otolemur garnettii ENSOGAG00000007074 I 0.825
ENSMPUG00000005002 Mustela putorius furo ENSMPUG00000005002 I 0.825
ZNF653 Myotis lucifugus ENSMLUG00000016337 I 0.825
ZNF653 Felis catus ENSFCAG00000004922 I 0.825
ZNF653 Sus scrofa ENSSSCG00000013616 I 0.825
ENSAMEG00000010478 Ailuropoda melanoleuca ENSAMEG00000010478 I 0.825
ZNF653 Tursiops truncatus ENSTTRG00000001794 I 0.825
ZNF653 Canis familiaris ENSCAFG00000031712 I 0.825
ZNF653 Cavia porcellus ENSCPOG00000010842 I 0.825
ENSACAG00000016965 Anolis carolinensis ENSACAG00000016965 I 0.823
Ogr06398 Ophisaurus gracilis Ogr06398 I 0.823
Pvit_14576 Pogona vitticeps Pvit_14576 I 0.823
ENSMMUP00000027145 Macaca fascicularis ENSMMUP00000027145 I 0.819
Zfp653 Dipodomys ordii ENSDORG00000007511 I 0.814
Alligator_sinensis_CCG017936.1 Alligator sinensis Alligator_sinensis_CCG017936.1 I 0.812
Cmyd_10005916 Chelonia mydas Cmyd_10005916 I 0.811
ENSOANG00000012102 Ornithorhynchus anatinus ENSOANG00000012102 I 0.811
ENSLACG00000017182 Latimeria chalumnae ENSLACG00000017182 I 0.811
znf653 Oryzias latipes ENSORLG00000016563 I 0.793
ENSONIG00000008038 Oreochromis niloticus ENSONIG00000008038 I 0.793
ENSPFOG00000003530 Poecilia formosa ENSPFOG00000003530 I 0.793
ENSAMXG00000005448 Astyanax mexicanus ENSAMXG00000005448 I 0.793
znf653 Danio rerio ENSDARG00000093469 I 0.789
ENSSTOG00000003640 Ictidomys tridecemlineatus ENSSTOG00000003640 I 0.779