ZNF148 (Homo sapiens)

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000163848 T095021_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. [provided by RefSeq, Feb 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Homo sapiens Transfac license required
Transfac license required
Matys et al.(2006)
(Direct) (Direct)
Homo sapiens Transfac license required
Transfac license required
Matys et al.(2006)
(Direct) (Direct)
Homo sapiens Transfac license required
Transfac license required
Matys et al.(2006)
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000353863 C2H2 ZF 171 193
ENSP00000353863 C2H2 ZF 199 221
ENSP00000353863 C2H2 ZF 227 249
ENSP00000353863 C2H2 ZF 255 278
ENSP00000419322 C2H2 ZF 171 193
ENSP00000419322 C2H2 ZF 199 221
ENSP00000419322 C2H2 ZF 227 249
ENSP00000419322 C2H2 ZF 255 278
ENSP00000420102 C2H2 ZF 7 29
ENSP00000420335 C2H2 ZF 171 193
ENSP00000420335 C2H2 ZF 199 221
ENSP00000420335 C2H2 ZF 227 249
ENSP00000420335 C2H2 ZF 255 278
ENSP00000420448 C2H2 ZF 171 193
ENSP00000420448 C2H2 ZF 199 221
ENSP00000420448 C2H2 ZF 227 249
ENSP00000420448 C2H2 ZF 255 278
ENSP00000437916 C2H2 ZF 171 193
ENSP00000437916 C2H2 ZF 199 221
ENSP00000437916 C2H2 ZF 227 249
ENSP00000437916 C2H2 ZF 255 278


Other C2H2 ZF family TFs
Other Homo sapiens TFs

67 Related TFs

Name Species Gene ID Motif Evidence SR
Afo_R004007 Aptenodytes forsteri Afo_R004007 I 0.759
Aan_R014758 Calypte anna Aan_R014758 I 0.759
Aan_R003668 Calypte anna Aan_R003668 I 0.827
ZNF148 Tursiops truncatus ENSTTRG00000014714 I 0.827
znf148 Takifugu rubripes ENSTRUG00000006270 I 0.810
ZNF281 Taeniopygia guttata ENSTGUG00000004438 I 0.759
ZNF148 Taeniopygia guttata ENSTGUG00000004010 I 0.827
ZNF148 Tupaia belangeri ENSTBEG00000008435 I 0.827
ENSSTOG00000027082 Ictidomys tridecemlineatus ENSSTOG00000027082 I 0.827
ZNF148 Sus scrofa ENSSSCG00000011858 I 0.827
ENSSHAG00000013855 Sarcophilus harrisii ENSSHAG00000013855 I 0.827
ZNF148 Sorex araneus ENSSARG00000007257 I 0.827
Zfp148 Rattus norvegicus ENSRNOG00000001789 I 0.827
ZNF148 Pteropus vampyrus ENSPVAG00000006133 I 0.827
ENSPSIG00000003614 Pelodiscus sinensis ENSPSIG00000003614 I 0.827
Afo_R008251 Aptenodytes forsteri Afo_R008251 I 0.827
Alligator_sinensis_CCG011250.1 Alligator sinensis Alligator_sinensis_CCG011250.1 I 0.759
znf148 Xenopus tropicalis XB-GENE-996852 I 0.815
Tal_R010256 Tyto alba Tal_R010256 I 0.827
Tal_R010113 Tyto alba Tal_R010113 I 0.759
Pvit_14619 Pogona vitticeps Pvit_14619 I 0.759
Pvit_03082 Pogona vitticeps Pvit_03082 I 0.815
Ogr00130 Ophisaurus gracilis Ogr00130 I 0.762
Gfo_R006633 Geospiza fortis Gfo_R006633 I 0.759
Gfo_R001184 Geospiza fortis Gfo_R001184 I 0.827
ENSP00000420448 Macaca fascicularis ENSP00000420448 I 0.827
ENSP00000420448-D1 Bos grunniens ENSP00000420448-D1 I 0.827
Cmyd_10021057 Chelonia mydas Cmyd_10021057 I 0.759
Cmyd_10009615 Chelonia mydas Cmyd_10009615 I 0.827
Brh_R005182 Buceros rhinoceros Brh_R005182 I 0.759
Brh_R001493 Buceros rhinoceros Brh_R001493 I 0.827
Alligator_sinensis_CCG014066.1 Alligator sinensis Alligator_sinensis_CCG014066.1 I 0.815
ENSPPYG00000013462 Pongo abelii ENSPPYG00000013462 I 0.827
ENSPFOG00000004115 Poecilia formosa ENSPFOG00000004115 I 0.822
ZNF148 Felis catus ENSFCAG00000026852 I 0.827
ENSFALG00000014467 Ficedula albicollis ENSFALG00000014467 I 0.759
ENSFALG00000013520 Ficedula albicollis ENSFALG00000013520 I 0.827
ZNF148 Echinops telfairi ENSETEG00000002856 I 0.827
ZNF148 Equus caballus ENSECAG00000013557 I 0.827
ENSDORG00000003955 Dipodomys ordii ENSDORG00000003955 I 0.827
ZNF148 Dasypus novemcinctus ENSDNOG00000000280 I 0.827
znf148 Danio rerio ENSDARG00000055106 I 0.810
ZNF148 Callithrix jacchus ENSCJAG00000006741 I 0.827
ZNF148 Canis familiaris ENSCAFG00000012574 I 0.827
ZNF148 Bos taurus ENSBTAG00000040031 I 0.827
ENSAPLG00000008859 Anas platyrhynchos ENSAPLG00000008859 I 0.827
ENSAMXG00000006043 Astyanax mexicanus ENSAMXG00000006043 I 0.813
ENSAMEG00000004258 Ailuropoda melanoleuca ENSAMEG00000004258 I 0.827
ZNF281 Anolis carolinensis ENSACAG00000006286 I 0.759
ZNF148 Gallus gallus ENSGALG00000012049 I 0.827
ENSLACG00000006364 Latimeria chalumnae ENSLACG00000006364 I 0.815
ENSPANG00000004284 Papio anubis ENSPANG00000004284 I 0.827
znf148 Oryzias latipes ENSORLG00000015950 I 0.810
ZNF148 Ochotona princeps ENSOPRG00000010519 I 0.772
ENSONIG00000004240 Oreochromis niloticus ENSONIG00000004240 I 0.822
ZNF148 Otolemur garnettii ENSOGAG00000013652 I 0.827
ENSOARG00000020237 Ovis aries ENSOARG00000020237 I 0.827
ZNF281 Ornithorhynchus anatinus ENSOANG00000004857 I 0.759
ENSNLEG00000000773 Nomascus leucogenys ENSNLEG00000000773 I 0.827
Zfp148 Mus musculus ENSMUSG00000022811 I 0.827
ENSMPUG00000004162 Mustela putorius furo ENSMPUG00000004162 I 0.827
ZNF148 Monodelphis domestica ENSMODG00000018374 I 0.827
ZNF148 Macaca mulatta ENSMMUG00000001169 I 0.827
ENSLOCG00000002769 Lepisosteus oculatus ENSLOCG00000002769 I 0.822
ZNF148 Loxodonta africana ENSLAFG00000016025 I 0.827
ZNF148 Anolis carolinensis ENSACAG00000010047 I 0.815