ZNF558 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000167785 T095063_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF558
M07620_2.00		 Homo sapiens
HKGRAYHTGTRGRTKBATRYCTTYCAK
MTGRAAGRYATVMAYCYACADRTYCMD		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF558.RCADE.ReprocessedData		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000301475 C2H2 ZF 153 174
ENSP00000301475 C2H2 ZF 180 202
ENSP00000301475 C2H2 ZF 208 230
ENSP00000301475 C2H2 ZF 236 258
ENSP00000301475 C2H2 ZF 264 286
ENSP00000301475 C2H2 ZF 292 314
ENSP00000301475 C2H2 ZF 320 342
ENSP00000301475 C2H2 ZF 348 370
ENSP00000301475 C2H2 ZF 376 398
ENSP00000471277 C2H2 ZF 153 174
ENSP00000471277 C2H2 ZF 180 202
ENSP00000471277 C2H2 ZF 208 230
ENSP00000471277 C2H2 ZF 236 258
ENSP00000471277 C2H2 ZF 264 286
ENSP00000471277 C2H2 ZF 292 314
ENSP00000471277 C2H2 ZF 320 342
ENSP00000471277 C2H2 ZF 348 370
ENSP00000471277 C2H2 ZF 376 398

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

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25 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action