ZBTB49 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000168826 T095072_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor binding activity; sequence-specific DNA binding activity; and transcription coactivator binding activity. Involved in negative regulation of cell population proliferation; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle. Located in cytosol; microtubule cytoskeleton; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZBTB49
M02901_2.00		 Homo sapiens
TTYYGCYTGRCVBGTCA
TGACVBGYCARGCRRAA		 SELEX
Jolma et al.(2013)
ZBTB49_1		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000338807 C2H2 ZF 395 417
ENSP00000338807 C2H2 ZF 423 445
ENSP00000338807 C2H2 ZF 451 473
ENSP00000338807 C2H2 ZF 479 501
ENSP00000338807 C2H2 ZF 507 529
ENSP00000338807 C2H2 ZF 535 557
ENSP00000338807 C2H2 ZF 563 585
ENSP00000421654 C2H2 ZF 132 154
ENSP00000421654 C2H2 ZF 156 172
ENSP00000422321 C2H2 ZF 395 417
ENSP00000426765 C2H2 ZF 97 119

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

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50 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action