ZNF449 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000173275 T095127_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a nuclear protein that likely functions as a transcription factor. The protein includes an N-terminal SCAN domain, and seven C2H2-type zinc finger motifs. [provided by RefSeq, May 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF449
M04560_2.00		 Homo sapiens
NTGYTKGCWCGCGAB
VTCGCGWGCMARCAN		 SELEX
Yin et al.(2017)
ZNF449_eDBD_HT-SELEX_1		 (Direct) (Direct)
ZNF449
M04561_2.00		 Homo sapiens
RCGCCCAACC
GGTTGGGCGY		 SELEX
Yin et al.(2017)
ZNF449_eDBD_HT-SELEX_2		 (Direct) (Direct)
ZNF449
M04562_2.00		 Homo sapiens
MMGCCCMACC
GGTKGGGCKK		 SELEX
Yin et al.(2017)
ZNF449_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
ZNF449
M04563_2.00		 Homo sapiens
NTGYTKGCDCGCGWB
VWCGCGHGCMARCAN		 SELEX
Yin et al.(2017)
ZNF449_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
ZNF449
M08344_2.00		 Homo sapiens
NNVAGCCCARCCHNNNNNNNN
NNNNNNNNDGGYTGGGCTBNN		 ChIP-seq
Schmitges et al.(2016)
Q6P9G9_1-7.RCADE		 (Direct) (Direct)
ZNF449
M08922_2.00		 Homo sapiens
VAGCCCARCCN
NGGYTGGGCTB		 Misc
Kulakovskiy et al.(2013)
ZN449_HUMAN.H11MO.0.C		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000339585 C2H2 ZF 323 345
ENSP00000339585 C2H2 ZF 351 373
ENSP00000339585 C2H2 ZF 379 401
ENSP00000339585 C2H2 ZF 407 429
ENSP00000339585 C2H2 ZF 435 457
ENSP00000339585 C2H2 ZF 463 485
ENSP00000339585 C2H2 ZF 491 513

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

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33 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action