ZNF449 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000173275 T095127_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a nuclear protein that likely functions as a transcription factor. The protein includes an N-terminal SCAN domain, and seven C2H2-type zinc finger motifs. [provided by RefSeq, May 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF449
M04560_2.00
Homo sapiens
NTGYTKGCWCGCGAB

VTCGCGWGCMARCAN
SELEX
Yin et al.(2017)
ZNF449_eDBD_HT-SELEX_1
(Direct) (Direct)
ZNF449
M04561_2.00
Homo sapiens
RCGCCCAACC

GGTTGGGCGY
SELEX
Yin et al.(2017)
ZNF449_eDBD_HT-SELEX_2
(Direct) (Direct)
ZNF449
M04562_2.00
Homo sapiens
MMGCCCMACC

GGTKGGGCKK
SELEX
Yin et al.(2017)
ZNF449_eDBD_Methyl-HT-SELEX_1
(Direct) (Direct)
ZNF449
M04563_2.00
Homo sapiens
NTGYTKGCDCGCGWB

VWCGCGHGCMARCAN
SELEX
Yin et al.(2017)
ZNF449_eDBD_Methyl-HT-SELEX_2
(Direct) (Direct)
ZNF449
M08344_2.00
Homo sapiens
NNVAGCCCARCCHNNNNNNNN

NNNNNNNNDGGYTGGGCTBNN
ChIP-seq
Schmitges et al.(2016)
Q6P9G9_1-7.RCADE
(Direct) (Direct)
ZNF449
M08922_2.00
Homo sapiens
VAGCCCARCCN

NGGYTGGGCTB
Misc
Kulakovskiy et al.(2013)
ZN449_HUMAN.H11MO.0.C
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000339585 C2H2 ZF 323 345
ENSP00000339585 C2H2 ZF 351 373
ENSP00000339585 C2H2 ZF 379 401
ENSP00000339585 C2H2 ZF 407 429
ENSP00000339585 C2H2 ZF 435 457
ENSP00000339585 C2H2 ZF 463 485
ENSP00000339585 C2H2 ZF 491 513

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

33 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Aan_R004160 Calypte anna Aan_R004160 I 0.000
Afo_R013414 Aptenodytes forsteri Afo_R013414 I 0.000
Brh_R001802 Buceros rhinoceros Brh_R001802 I 0.000
CLOCK Procavia capensis ENSPCAG00000001407 I 0.000
CLOCK Pteropus vampyrus ENSPVAG00000008960 I 0.000
CLOCK Loxodonta africana ENSLAFG00000009558 I 0.000
Clock Rattus norvegicus ENSRNOG00000002175 I 0.000
CLOCK Sorex araneus ENSSARG00000002584 I 0.000
CLOCK Gorilla gorilla ENSGGOG00000005753 I 0.000
CLOCK Anolis carolinensis ENSACAG00000009335 I 0.000
CLOCK Meleagris gallopavo ENSMGAG00000011742 I 0.000
CLOCK Myotis lucifugus ENSMLUG00000010007 I 0.000
CLOCK Macaca mulatta ENSMMUG00000001919 I 0.000
CLOCK Monodelphis domestica ENSMODG00000020678 I 0.000
CLOCK Ochotona princeps ENSOPRG00000005292 I 0.000
Clock Mus musculus ENSMUSG00000029238 D 0.000
CLOCK Ornithorhynchus anatinus ENSOANG00000003801 I 0.000
CLOCK Otolemur garnettii ENSOGAG00000012464 I 0.000
CLOCK Gallus gallus ENSGALG00000013793 I 0.000
CLOCK Sus scrofa ENSSSCG00000008909 I 0.000
clock Xenopus tropicalis XB-GENE-495448 I 0.000
CLOCK Vicugna pacos ENSVPAG00000006438 I 0.000
CLOCK Bos taurus ENSBTAG00000044044 I 0.000
CLOCK Canis familiaris ENSCAFG00000002140 I 0.000
CLOCK Callithrix jacchus ENSCJAG00000018261 I 0.000
CLOCK Cavia porcellus ENSCPOG00000011807 I 0.000
CLOCK Pan troglodytes ENSPTRG00000016072 I 0.000
CLOCK Tursiops truncatus ENSTTRG00000000960 I 0.000
CLOCK Dasypus novemcinctus ENSDNOG00000018101 I 0.000
CLOCK Equus caballus ENSECAG00000006331 I 0.000
CLOCK Echinops telfairi ENSETEG00000015604 I 0.000
CLOCK Tupaia belangeri ENSTBEG00000002540 I 0.000
CLOCK Felis catus ENSFCAG00000001064 I 0.000
CLOCK Homo sapiens ENSG00000134852 D 0.000
CLOCK Oryctolagus cuniculus ENSOCUG00000022350 I 0.000
clock.L Xenopus laevis XB-GENE-6254406 I 0.000
clocka Tetraodon nigroviridis ENSTNIG00000004102 I 0.000
clocka Gasterosteus aculeatus ENSGACG00000015939 I 0.000
clocka Takifugu rubripes ENSTRUG00000001837 I 0.000
clocka Oryzias latipes ENSORLG00000004495 I 0.000
clocka Danio rerio ENSDARG00000011703 I 0.000
clockb Tetraodon nigroviridis ENSTNIG00000017652 I 0.000
clockb Danio rerio ENSDARG00000003631 I 0.000
clockb Takifugu rubripes ENSTRUG00000015488 I 0.000
ENSAMEG00000018420 Ailuropoda melanoleuca ENSAMEG00000018420 I 0.000
ENSAMXG00000005565 Astyanax mexicanus ENSAMXG00000005565 I 0.000
ENSAMXG00000021792 Astyanax mexicanus ENSAMXG00000021792 I 0.000
ENSAPLG00000007176 Anas platyrhynchos ENSAPLG00000007176 I 0.000
ENSCSAG00000005019 Chlorocebus sabaeus ENSCSAG00000005019 I 0.000
ENSFALG00000003646 Ficedula albicollis ENSFALG00000003646 I 0.000
ENSGMOG00000004825 Gadus morhua ENSGMOG00000004825 I 0.000
ENSLACG00000013436 Latimeria chalumnae ENSLACG00000013436 I 0.000
ENSLOCG00000014043 Lepisosteus oculatus ENSLOCG00000014043 I 0.000
ENSMEUG00000005481 Macropus eugenii ENSMEUG00000005481 I 0.000
ENSMMUP00000002568 Macaca fascicularis ENSMMUP00000002568 I 0.000
ENSMPUG00000005091 Mustela putorius furo ENSMPUG00000005091 I 0.000
ENSNLEG00000008499 Nomascus leucogenys ENSNLEG00000008499 I 0.000
ENSOARG00000001602 Ovis aries ENSOARG00000001602 I 0.000
ENSONIG00000002943 Oreochromis niloticus ENSONIG00000002943 I 0.000
ENSONIG00000008797 Oreochromis niloticus ENSONIG00000008797 I 0.000
ENSP00000370723-D1 Bos grunniens ENSP00000370723-D1 I 0.000
ENSPANG00000006882 Papio anubis ENSPANG00000006882 I 0.000
ENSPFOG00000015083 Poecilia formosa ENSPFOG00000015083 I 0.000
ENSPFOG00000017215 Poecilia formosa ENSPFOG00000017215 I 0.000
ENSPPYG00000014762 Pongo abelii ENSPPYG00000014762 I 0.000
ENSPSIG00000011404 Pelodiscus sinensis ENSPSIG00000011404 I 0.000
ENSSHAG00000005555 Sarcophilus harrisii ENSSHAG00000005555 I 0.000
ENSSTOG00000016179 Ictidomys tridecemlineatus ENSSTOG00000016179 I 0.000
ENSTGUG00000007495 Taeniopygia guttata ENSTGUG00000007495 I 0.000
ENSTSYG00000003546 Tarsius syrichta ENSTSYG00000003546 I 0.000
ENSXMAG00000016928 Xiphophorus maculatus ENSXMAG00000016928 I 0.000
ENSXMAG00000017672 Xiphophorus maculatus ENSXMAG00000017672 I 0.000
Gfo_R010434 Geospiza fortis Gfo_R010434 I 0.000
Ogr11799 Ophisaurus gracilis Ogr11799 I 0.000
Pvit_07605 Pogona vitticeps Pvit_07605 I 0.000
SNAPOd2T00001991001 Oikopleura dioica SNAPOd2T00001991001 I 0.000
Tal_R002573 Tyto alba Tal_R002573 I 0.000