ZNF454 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000178187 T095166_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF454
M04571_2.00
Homo sapiens
WRGCGCCWGGCGCYW

WRGCGCCWGGCGCYW
SELEX
Yin et al.(2017)
ZNF454_eDBD_HT-SELEX_1
(Direct) (Direct)
ZNF454
M04572_2.00
Homo sapiens
TRGCGCCGGCGCYN

NRGCGCCGGCGCYA
SELEX
Yin et al.(2017)
ZNF454_eDBD_HT-SELEX_2
(Direct) (Direct)
ZNF454
M04573_2.00
Homo sapiens
WRGCGCCWGGCGCYW

WRGCGCCWGGCGCYW
SELEX
Yin et al.(2017)
ZNF454_eDBD_Methyl-HT-SELEX_1
(Direct) (Direct)
ZNF454
M04574_2.00
Homo sapiens
TRGCGCCGGCGCYN

NRGCGCCGGCGCYA
SELEX
Yin et al.(2017)
ZNF454_eDBD_Methyl-HT-SELEX_2
(Direct) (Direct)
ZNF454
M07651_2.00
Homo sapiens
CRKVVRHCCVYCRGGVCCBVGAGCCNKYB

VRMNGGCTCBVGGBCCYGRBRGDYBBMYG
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF454.MEME.OriginalMapping
(Direct) (Direct)
ZNF454
M08256_2.00
Homo sapiens
GWGCYTT

AARGCWC
ChIP-seq
Najafabadi et al.(2015b)
ZNF454
(Direct) (Direct)
ZNF454
M08346_2.00
Homo sapiens
KVVRNCHNYMRGGGCCNDGDGCCWTTB

VAAWGGCHCHNGGCCCYKRNDGNYBBM
ChIP-seq
Schmitges et al.(2016)
Q8N9F8_4-12.RCADE
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000326249 C2H2 ZF 178 200
ENSP00000326249 C2H2 ZF 216 238
ENSP00000326249 C2H2 ZF 244 266
ENSP00000326249 C2H2 ZF 272 294
ENSP00000326249 C2H2 ZF 300 322
ENSP00000326249 C2H2 ZF 328 350
ENSP00000326249 C2H2 ZF 356 378
ENSP00000326249 C2H2 ZF 384 406
ENSP00000326249 C2H2 ZF 412 434
ENSP00000326249 C2H2 ZF 440 462
ENSP00000326249 C2H2 ZF 468 490
ENSP00000326249 C2H2 ZF 496 518
ENSP00000430354 C2H2 ZF 178 200
ENSP00000430354 C2H2 ZF 216 238
ENSP00000430354 C2H2 ZF 244 266
ENSP00000430354 C2H2 ZF 272 294
ENSP00000430354 C2H2 ZF 300 322
ENSP00000430354 C2H2 ZF 328 350
ENSP00000430354 C2H2 ZF 356 378
ENSP00000430354 C2H2 ZF 384 406
ENSP00000430354 C2H2 ZF 412 434
ENSP00000430354 C2H2 ZF 440 462
ENSP00000430354 C2H2 ZF 468 490
ENSP00000430354 C2H2 ZF 496 518

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

27 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZNF454 Bos taurus ENSBTAG00000004262 I 0.827
ZNF454 Gorilla gorilla ENSGGOG00000022508 I 0.827
ENSNLEG00000001430 Nomascus leucogenys ENSNLEG00000001430 I 0.827
ENSCSAG00000008562 Chlorocebus sabaeus ENSCSAG00000008562 I 0.827
ZNF454 Pteropus vampyrus ENSPVAG00000007676 I 0.827
ENSBTAP00000016859-D1 Bos grunniens ENSBTAP00000016859-D1 I 0.827
ZNF454 Pan troglodytes ENSPTRG00000017611 I 0.827
ZNF454 Callithrix jacchus ENSCJAG00000018857 I 0.826
ENSOARG00000004411 Ovis aries ENSOARG00000004411 I 0.826
ENSMPUG00000000725 Mustela putorius furo ENSMPUG00000000725 I 0.825
ZNF454 Canis familiaris ENSCAFG00000031168 I 0.825
ZNF454 Felis catus ENSFCAG00000021971 I 0.823
ZNF454 Tursiops truncatus ENSTTRG00000012880 I 0.823
ENSPANG00000009509 Papio anubis ENSPANG00000009509 I 0.821
ZNF454 Erinaceus europaeus ENSEEUG00000007684 I 0.821
ZNF454 Choloepus hoffmanni ENSCHOG00000002770 I 0.820
ENSP00000326249 Macaca fascicularis ENSP00000326249 I 0.818
ZNF454 Myotis lucifugus ENSMLUG00000002894 I 0.818
ENSMMUG00000008980 Macaca mulatta ENSMMUG00000008980 I 0.818
ZNF454 Ochotona princeps ENSOPRG00000009035 I 0.811
ZNF454 Equus caballus ENSECAG00000005115 I 0.806
ZNF454 Sus scrofa ENSSSCG00000027351 I 0.798
ZNF454 Oryctolagus cuniculus ENSOCUG00000029119 I 0.794
ZNF454 Tupaia belangeri ENSTBEG00000000346 I 0.792
Zfp454 Mus musculus ENSMUSG00000048728 I 0.781
Znf454 Rattus norvegicus ENSRNOG00000022971 I 0.773