ZBTB7A (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000178951 T095173_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables several functions, including SMAD binding activity; androgen receptor binding activity; and transcription corepressor binding activity. Involved in several processes, including erythrocyte maturation; negative regulation of signal transduction; and regulation of nucleobase-containing compound metabolic process. Located in cytoplasm and nucleus. Colocalizes with DNA-dependent protein kinase complex and NuRD complex. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZBTB7A
M02914_2.00		 Homo sapiens
NRCGACCACCNV
BNGGTGGTCGYN		 SELEX
Jolma et al.(2013)
ZBTB7A_1		 (Direct) (Direct)
ZBTB7A
M04579_2.00		 Homo sapiens
DCGACCMCCVH
DBGGKGGTCGH		 SELEX
Yin et al.(2017)
ZBTB7A_eDBD_HT-SELEX		 (Direct) (Direct)
ZBTB7A
M04580_2.00		 Homo sapiens
DCGACCACCNH
DNGGTGGTCGH		 SELEX
Yin et al.(2017)
ZBTB7A_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
ZBTB7A
M07937_2.00		 Homo sapiens
SNVVGMCCCYNNSBS
SVSNNRGGGKCBBNS		 ChIP-seq
Gerstein et al.(2012)
K562_ZBTB7A_HudsonAlpha		 (Direct) (Direct)
ZBTB7A
M08095_2.00		 Homo sapiens
NBSRCTTCCGGNN
NNCCGGAAGYSVN		 ChIP-seq
Mathelier et al.(2014)
MA0750.2		 (Direct) (Direct)
ZBTB7A
M08926_2.00		 Homo sapiens
VVGMCCCYB
VRGGGKCBB		 Misc
Kulakovskiy et al.(2013)
ZBT7A_HUMAN.H11MO.0.A		 (Direct) (Direct)
ZBTB7A
M10273_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LRF_Q2		 (Direct) (Direct)
ZBTB7A
M10274_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LRF_Q3		 (Direct) (Direct)
ZBTB7A
M10275_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$LRF_Q6		 (Direct) (Direct)
ZBTB7A
M10276_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ZBTB7A_02		 (Direct) (Direct)
ZBTB7A
M10277_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ZBTB7A_03		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zbtb7a
M08991_2.00 		Mus musculus
VVGMCCCYB
VRGGGKCBB		 Misc
Kulakovskiy et al.(2013)
ZBT7A_MOUSE.H11MO.0.B 		0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000323670 C2H2 ZF 382 404
ENSP00000323670 C2H2 ZF 410 432
ENSP00000323670 C2H2 ZF 438 460
ENSP00000323670 C2H2 ZF 466 487
ENSP00000471865 C2H2 ZF 382 404
ENSP00000471865 C2H2 ZF 410 432
ENSP00000471865 C2H2 ZF 438 460
ENSP00000471865 C2H2 ZF 466 487

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

42 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action