ZNF154 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000179909 T095180_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a protein that belongs to the zinc finger Kruppel family of transcriptional regulators, whose members are thought to function in normal and abnormal cell growth and differentiation. Hypermethylation of this gene is associated with the recurrence of non muscle invasive bladder cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF154
M07656_2.00
Homo sapiens
TGTCTAGTARRTCYD

HRGAYYTACTAGACA
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF154.RCADE.ReprocessedData
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000421258 C2H2 ZF 161 183
ENSP00000421258 C2H2 ZF 189 211
ENSP00000421258 C2H2 ZF 217 239
ENSP00000421258 C2H2 ZF 245 267
ENSP00000421258 C2H2 ZF 273 295
ENSP00000421258 C2H2 ZF 301 323
ENSP00000421258 C2H2 ZF 329 351
ENSP00000421258 C2H2 ZF 357 379
ENSP00000421258 C2H2 ZF 385 407
ENSP00000421258 C2H2 ZF 413 435
ENSP00000469633 C2H2 ZF 161 183
ENSP00000469633 C2H2 ZF 189 211
ENSP00000469633 C2H2 ZF 217 239
ENSP00000469633 C2H2 ZF 245 267
ENSP00000469633 C2H2 ZF 273 295
ENSP00000469633 C2H2 ZF 301 323
ENSP00000469633 C2H2 ZF 329 351
ENSP00000469633 C2H2 ZF 357 379
ENSP00000469633 C2H2 ZF 385 407
ENSP00000469633 C2H2 ZF 413 435

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

18 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZNF154 Pan troglodytes ENSPTRG00000011568 I 0.825
ZNF154 Gorilla gorilla ENSGGOG00000005310 I 0.825
ENSNLEG00000010994 Nomascus leucogenys ENSNLEG00000010994 I 0.825
ENSPANG00000026076 Papio anubis ENSPANG00000026076 I 0.824
ENSP00000412998 Macaca fascicularis ENSP00000412998 I 0.824
ENSCSAG00000001621 Chlorocebus sabaeus ENSCSAG00000001621 I 0.818
ZNF671 Macaca mulatta ENSMMUG00000023357 I 0.801
ENSTSYG00000010318 Tarsius syrichta ENSTSYG00000010318 I 0.781
ENSOCUG00000029338 Oryctolagus cuniculus ENSOCUG00000029338 I 0.769
ZNF154 Tursiops truncatus ENSTTRG00000016326 I 0.763
ENSVPAG00000004611 Vicugna pacos ENSVPAG00000004611 I 0.763
ZNF154 Otolemur garnettii ENSOGAG00000003901 I 0.762
ENSOARG00000003749 Ovis aries ENSOARG00000003749 I 0.761
ENSP00000337555-D12 Bos grunniens ENSP00000337555-D12 I 0.760
ZNF551 Bos taurus ENSBTAG00000003447 I 0.760
ZNF154 Tupaia belangeri ENSTBEG00000004631 I 0.758
ZNF154 Pteropus vampyrus ENSPVAG00000013523 I 0.756