ZSCAN4 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000180532 T095190_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZSCAN4
M02919_2.00
Homo sapiens
YGCACACVCTGWAAR

YTTWCAGBGTGTGCR
SELEX
Jolma et al.(2013)
ZSCAN4_1
(Direct) (Direct)
ZSCAN4
M04593_2.00
Homo sapiens
NHGCACACVCTGNMANN

NNTKNCAGBGTGTGCDN
SELEX
Yin et al.(2017)
ZSCAN4_eDBD_HT-SELEX
(Direct) (Direct)
ZSCAN4
M04594_2.00
Homo sapiens
NYGCACACMCTGHMAVH

DBTKDCAGKGTGTGCRN
SELEX
Yin et al.(2017)
ZSCAN4_eDBD_Methyl-HT-SELEX
(Direct) (Direct)
ZSCAN4
M05852_2.00
Homo sapiens
RCACAYVCTBNMA

TKNVAGBRTGTGY
SMiLE-seq
Isakova et al.(2017)
ZSCAN4
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000321963 C2H2 ZF 312 334
ENSP00000321963 C2H2 ZF 340 362
ENSP00000321963 C2H2 ZF 368 390
ENSP00000321963 C2H2 ZF 396 418
ENSP00000480210 C2H2 ZF 312 334
ENSP00000480210 C2H2 ZF 340 362
ENSP00000480210 C2H2 ZF 368 390
ENSP00000480210 C2H2 ZF 396 418

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

9 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPPYG00000010476 Pongo abelii ENSPPYG00000010476 I 0.827
ZSCAN4 Pan troglodytes ENSPTRG00000011566 I 0.824
ENSPANG00000025039 Papio anubis ENSPANG00000025039 I 0.821
ZSCAN4 Macaca mulatta ENSMMUG00000005335 I 0.821
ENSP00000391414 Macaca fascicularis ENSP00000391414 I 0.821
ZSCAN4 Gorilla gorilla ENSGGOG00000005293 I 0.812
ENSCSAG00000001623 Chlorocebus sabaeus ENSCSAG00000001623 I 0.811
ENSNLEG00000010988 Nomascus leucogenys ENSNLEG00000010988 I 0.804