CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
Home
Tools
View cart
Bulk downloads
Database stats
Contact us
Help
Update Log
FAQ
Links
How to cite
PLAG1
(
Homo sapiens
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSG00000181690
T095205_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
PLAG1
M06465_2.00
Homo sapiens
CCCCCKWDGGCCCC
GGGGCCHWMGGGGG
B1H
Mathelier et al.(2014)
MA0163.1
(Direct)
(Direct)
PLAG1
M10286_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_01
(Direct)
(Direct)
PLAG1
M10287_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_02
(Direct)
(Direct)
PLAG1
M10288_2.00
Homo sapiens
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_08
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000325546
C2H2 ZF
34
56
FPCQLCDKAFNSVEKLKVHSYSH
ENSP00000325546
C2H2 ZF
62
86
YKCIQQDCTKAFVSKYKLQRHMATH
ENSP00000325546
C2H2 ZF
92
114
HKCNYCEKMFHRKDHLKNHLHTH
ENSP00000325546
C2H2 ZF
121
143
FKCEECGKNYNTKLGFKRHLALH
ENSP00000325546
C2H2 ZF
150
172
LTCKVCLQTFESTGVLLEHLKSH
ENSP00000325546
C2H2 ZF
185
207
HQCEHCDRRFYTRKDVRRHMVVH
ENSP00000325546
C2H2 ZF
213
236
FLCQYCAQRFGRKDHLTRHMKKSH
ENSP00000404067
C2H2 ZF
10
32
HKCNYCEKMFHRKDHLKNHLHTH
ENSP00000404067
C2H2 ZF
39
61
FKCEECGKNYNTKLGFKRHLALH
ENSP00000404067
C2H2 ZF
68
90
LTCKVCLQTFESTGVLLEHLKSH
ENSP00000404067
C2H2 ZF
103
125
HQCEHCDRRFYTRKDVRRHMVVH
ENSP00000404067
C2H2 ZF
131
154
FLCQYCAQRFGRKDHLTRHMKKSH
ENSP00000416537
C2H2 ZF
34
56
FPCQLCDKAFNSVEKLKVHSYSH
ENSP00000416537
C2H2 ZF
62
86
YKCIQQDCTKAFVSKYKLQRHMATH
ENSP00000416537
C2H2 ZF
92
114
HKCNYCEKMFHRKDHLKNHLHTH
ENSP00000416537
C2H2 ZF
121
143
FKCEECGKNYNTKLGFKRHLALH
ENSP00000416537
C2H2 ZF
150
172
LTCKVCLQTFESTGVLLEHLKSH
ENSP00000416537
C2H2 ZF
185
207
HQCEHCDRRFYTRKDVRRHMVVH
ENSP00000416537
C2H2 ZF
213
236
FLCQYCAQRFGRKDHLTRHMKKSH
Links
Other
C2H2 ZF
family TFs
Other
Homo sapiens
TFs
57 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy