PLAG1 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000181690 T095205_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
PLAG1
M06465_2.00
Homo sapiens
CCCCCKWDGGCCCC

GGGGCCHWMGGGGG
B1H
Mathelier et al.(2014)
MA0163.1
(Direct) (Direct)
PLAG1
M10286_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_01
(Direct) (Direct)
PLAG1
M10287_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_02
(Direct) (Direct)
PLAG1
M10288_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_08
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000325546 C2H2 ZF 34 56
ENSP00000325546 C2H2 ZF 62 86
ENSP00000325546 C2H2 ZF 92 114
ENSP00000325546 C2H2 ZF 121 143
ENSP00000325546 C2H2 ZF 150 172
ENSP00000325546 C2H2 ZF 185 207
ENSP00000325546 C2H2 ZF 213 236
ENSP00000404067 C2H2 ZF 10 32
ENSP00000404067 C2H2 ZF 39 61
ENSP00000404067 C2H2 ZF 68 90
ENSP00000404067 C2H2 ZF 103 125
ENSP00000404067 C2H2 ZF 131 154
ENSP00000416537 C2H2 ZF 34 56
ENSP00000416537 C2H2 ZF 62 86
ENSP00000416537 C2H2 ZF 92 114
ENSP00000416537 C2H2 ZF 121 143
ENSP00000416537 C2H2 ZF 150 172
ENSP00000416537 C2H2 ZF 185 207
ENSP00000416537 C2H2 ZF 213 236

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

57 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Aan_R015460 Calypte anna Aan_R015460 I 0.817
Afo_R001782 Aptenodytes forsteri Afo_R001782 I 0.817
Brh_R011668 Buceros rhinoceros Brh_R011668 I 0.817
PLAG1 Anolis carolinensis ENSACAG00000017994 I 0.817
ENSAMEG00000006089 Ailuropoda melanoleuca ENSAMEG00000006089 I 0.827
ENSAPLG00000007090 Anas platyrhynchos ENSAPLG00000007090 I 0.810
PLAG1 Bos taurus ENSBTAG00000004022 I 0.820
PLAG1 Canis familiaris ENSCAFG00000007051 I 0.827
PLAG1 Choloepus hoffmanni ENSCHOG00000010218 I 0.808
PLAG1 Callithrix jacchus ENSCJAG00000016621 I 0.827
ENSCPOG00000008740 Cavia porcellus ENSCPOG00000008740 I 0.826
ENSCSAG00000014574 Chlorocebus sabaeus ENSCSAG00000014574 I 0.827
PLAG1 Dasypus novemcinctus ENSDNOG00000041438 N 0.827
Plag1 Dipodomys ordii ENSDORG00000011524 I 0.826
PLAG1 Equus caballus ENSECAG00000010773 I 0.827
PLAG1 Erinaceus europaeus ENSEEUG00000013472 I 0.827
ENSFALG00000010290 Ficedula albicollis ENSFALG00000010290 I 0.817
PLAG1 Felis catus ENSFCAG00000014980 I 0.827
PLAG1 Gallus gallus ENSGALG00000015407 I 0.817
PLAG1 Gorilla gorilla ENSGGOG00000026661 I 0.827
ENSLACG00000002568 Latimeria chalumnae ENSLACG00000002568 I 0.817
PLAG1 Loxodonta africana ENSLAFG00000013617 I 0.827
PLAG1 Meleagris gallopavo ENSMGAG00000011002 I 0.817
PLAG1 Myotis lucifugus ENSMLUG00000022542 I 0.827
ENSMMUG00000007346 Macaca mulatta ENSMMUG00000007346 I 0.827
ENSMPUG00000010446 Mustela putorius furo ENSMPUG00000010446 I 0.827
Plag1 Mus musculus ENSMUSG00000003282 I 0.823
ENSNLEG00000001218 Nomascus leucogenys ENSNLEG00000001218 I 0.827
ENSOANG00000005503 Ornithorhynchus anatinus ENSOANG00000005503 I 0.817
ENSOARG00000014951 Ovis aries ENSOARG00000014951 I 0.820
PLAG1 Oryctolagus cuniculus ENSOCUG00000006001 I 0.827
PLAG1 Otolemur garnettii ENSOGAG00000025403 I 0.819
ENSONIG00000009655 Oreochromis niloticus ENSONIG00000009655 I 0.780
plag1 Oryzias latipes ENSORLG00000019433 I 0.774
ENSP00000325546-D1 Bos grunniens ENSP00000325546-D1 I 0.820
ENSP00000416537 Macaca fascicularis ENSP00000416537 I 0.827
ENSPANG00000009705 Papio anubis ENSPANG00000009705 I 0.827
PLAG1 Procavia capensis ENSPCAG00000014102 I 0.827
ENSPPYG00000018602 Pongo abelii ENSPPYG00000018602 I 0.827
ENSPSIG00000017823 Pelodiscus sinensis ENSPSIG00000017823 I 0.817
PLAG1 Pan troglodytes ENSPTRG00000020266 I 0.827
PLAG1 Pteropus vampyrus ENSPVAG00000006397 N 0.827
Plag1 Rattus norvegicus ENSRNOG00000008846 I 0.823
ENSSHAG00000010371 Sarcophilus harrisii ENSSHAG00000010371 I 0.817
PLAG1 Sus scrofa ENSSSCG00000006247 I 0.827
ENSSTOG00000002716 Ictidomys tridecemlineatus ENSSTOG00000002716 I 0.827
PLAG1 Tupaia belangeri ENSTBEG00000013496 I 0.826
PLAG1 Taeniopygia guttata ENSTGUG00000011100 I 0.817
ENSTSYG00000013443 Tarsius syrichta ENSTSYG00000013443 I 0.827
PLAG1 Tursiops truncatus ENSTTRG00000016849 I 0.820
PLAG1 Vicugna pacos ENSVPAG00000010729 I 0.827
Gfo_R012674 Geospiza fortis Gfo_R012674 I 0.817
Myotis_brandtii_PLAG1_10024665 Myotis brandtii Myotis_brandtii_PLAG1_10024665 I 0.827
Pvit_07170 Pogona vitticeps Pvit_07170 I 0.817
Tal_R003136 Tyto alba Tal_R003136 I 0.817
plag1 Xenopus tropicalis XB-GENE-868443 I 0.782