PLAG1 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000181690 T095205_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
PLAG1
M06465_2.00
Homo sapiens
CCCCCKWDGGCCCC

GGGGCCHWMGGGGG
B1H
Mathelier et al.(2014)
MA0163.1
(Direct) (Direct)
PLAG1
M10286_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_01
(Direct) (Direct)
PLAG1
M10287_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_02
(Direct) (Direct)
PLAG1
M10288_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PLAG1_08
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000325546 C2H2 ZF 34 56
ENSP00000325546 C2H2 ZF 62 86
ENSP00000325546 C2H2 ZF 92 114
ENSP00000325546 C2H2 ZF 121 143
ENSP00000325546 C2H2 ZF 150 172
ENSP00000325546 C2H2 ZF 185 207
ENSP00000325546 C2H2 ZF 213 236
ENSP00000404067 C2H2 ZF 10 32
ENSP00000404067 C2H2 ZF 39 61
ENSP00000404067 C2H2 ZF 68 90
ENSP00000404067 C2H2 ZF 103 125
ENSP00000404067 C2H2 ZF 131 154
ENSP00000416537 C2H2 ZF 34 56
ENSP00000416537 C2H2 ZF 62 86
ENSP00000416537 C2H2 ZF 92 114
ENSP00000416537 C2H2 ZF 121 143
ENSP00000416537 C2H2 ZF 150 172
ENSP00000416537 C2H2 ZF 185 207
ENSP00000416537 C2H2 ZF 213 236

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

57 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action