WT1 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000184937 T095226_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
WT1
M00243_2.00		 Homo sapiens
NNNNNNN
NNNNNNN		 PBM
Barrera et al.(2016)
WT1_F392L		 (Direct) (Direct)
WT1
M00244_2.00		 Homo sapiens
NNNWAMWATATN
NATATWKTWNNN		 PBM
Barrera et al.(2016)
WT1_H373Y		 (Direct) (Direct)
WT1
M00245_2.00		 Homo sapiens
NNNNNNN
NNNNNNN		 PBM
Barrera et al.(2016)
WT1_R366C		 (Direct) (Direct)
WT1
M00246_2.00		 Homo sapiens
NNNNNNN
NNNNNNN		 PBM
Barrera et al.(2016)
WT1_R366L		 (Direct) (Direct)
WT1
M00247_2.00		 Homo sapiens
NWATATDAHNN
NNDTHATATWN		 PBM
Barrera et al.(2016)
WT1_R394L		 (Direct) (Direct)
WT1
M00248_2.00		 Homo sapiens
NNTATTWTATNNN
NNNATAWAATANN		 PBM
Barrera et al.(2016)
WT1_R394W		 (Direct) (Direct)
WT1
M00249_2.00		 Homo sapiens
NCYCCCCCVNN
NNBGGGGGRGN		 PBM
Barrera et al.(2016)
WT1_REF		 (Direct) (Direct)
WT1
M08937_2.00		 Homo sapiens
YYYCBBYYCCTCCYYCNCBY
RVGNGRRGGAGGRRVVGRRR		 Misc
Kulakovskiy et al.(2013)
WT1_HUMAN.H11MO.0.C		 (Direct) (Direct)
WT1
M10290_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$WT1_Q4		 (Direct) (Direct)
WT1
M10291_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$WT1_Q6_01		 (Direct) (Direct)
WT1
M10292_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$WT1_Q6_02		 (Direct) (Direct)
WT1
M10293_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$WT1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Wt1
M08968_2.00 		Mus musculus
YYYCBBYYCCTCCYYCNCBY
RVGNGRRGGAGGRRVVGRRR		 Misc
Kulakovskiy et al.(2013)
WT1_MOUSE.H11MO.0.B 		0.827 1.000
Wt1
M10337_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$WT1_02 		0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00243_2.00 C2H2 ZF 15 39
M00243_2.00 C2H2 ZF 45 69
M00243_2.00 C2H2 ZF 75 97
M00243_2.00 C2H2 ZF 103 127
M00244_2.00 C2H2 ZF 15 39
M00244_2.00 C2H2 ZF 45 69
M00244_2.00 C2H2 ZF 75 97
M00244_2.00 C2H2 ZF 103 127
M00245_2.00 C2H2 ZF 15 39
M00245_2.00 C2H2 ZF 45 69
M00245_2.00 C2H2 ZF 75 97
M00245_2.00 C2H2 ZF 103 127
M00246_2.00 C2H2 ZF 15 39
M00246_2.00 C2H2 ZF 45 69
M00246_2.00 C2H2 ZF 75 97
M00246_2.00 C2H2 ZF 103 127
M00247_2.00 C2H2 ZF 15 39
M00247_2.00 C2H2 ZF 45 69
M00247_2.00 C2H2 ZF 75 97
M00247_2.00 C2H2 ZF 103 127
M00248_2.00 C2H2 ZF 15 39
M00248_2.00 C2H2 ZF 45 69
M00248_2.00 C2H2 ZF 75 97
M00248_2.00 C2H2 ZF 103 127
M00249_2.00 C2H2 ZF 15 39
M00249_2.00 C2H2 ZF 45 69
M00249_2.00 C2H2 ZF 75 97
M00249_2.00 C2H2 ZF 103 127

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000331327 C2H2 ZF 391 415
ENSP00000331327 C2H2 ZF 421 445
ENSP00000331327 C2H2 ZF 451 473
ENSP00000331327 C2H2 ZF 482 506
ENSP00000368370 C2H2 ZF 179 203
ENSP00000368370 C2H2 ZF 209 233
ENSP00000368370 C2H2 ZF 239 261
ENSP00000368370 C2H2 ZF 267 291
ENSP00000413452 C2H2 ZF 391 415
ENSP00000413452 C2H2 ZF 421 445
ENSP00000413452 C2H2 ZF 451 473
ENSP00000413452 C2H2 ZF 479 503
ENSP00000415516 C2H2 ZF 374 398
ENSP00000415516 C2H2 ZF 404 428
ENSP00000415516 C2H2 ZF 434 456
ENSP00000415516 C2H2 ZF 462 486
ENSP00000435307 C2H2 ZF 162 186
ENSP00000435307 C2H2 ZF 192 216
ENSP00000435307 C2H2 ZF 222 244
ENSP00000435624 C2H2 ZF 82 106
ENSP00000435624 C2H2 ZF 112 134
ENSP00000435624 C2H2 ZF 143 167
ENSP00000436292 C2H2 ZF 1 24

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

77 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action