ZNF197 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000186448 T095249_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Naturally-occurring readthrough transcription is observed between this gene and the upstream zinc finger protein 660 gene and is represented by GeneID:110354863. [provided by RefSeq, May 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF197
M07684_2.00
Homo sapiens
YBBBYYYYTGWCYYY

RRRGWCARRRRVVVR
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF197.RCADE.ReprocessedData
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000345809 C2H2 ZF 370 392
ENSP00000345809 C2H2 ZF 398 420
ENSP00000345809 C2H2 ZF 426 448
ENSP00000345809 C2H2 ZF 454 476
ENSP00000345809 C2H2 ZF 482 504
ENSP00000345809 C2H2 ZF 510 532
ENSP00000345809 C2H2 ZF 538 560
ENSP00000345809 C2H2 ZF 566 588
ENSP00000345809 C2H2 ZF 594 616
ENSP00000345809 C2H2 ZF 622 644
ENSP00000345809 C2H2 ZF 650 672
ENSP00000345809 C2H2 ZF 678 700
ENSP00000345809 C2H2 ZF 706 728
ENSP00000345809 C2H2 ZF 734 756
ENSP00000345809 C2H2 ZF 762 784
ENSP00000345809 C2H2 ZF 790 812
ENSP00000345809 C2H2 ZF 818 840
ENSP00000345809 C2H2 ZF 846 868
ENSP00000345809 C2H2 ZF 874 896
ENSP00000345809 C2H2 ZF 902 924
ENSP00000345809 C2H2 ZF 930 952
ENSP00000345809 C2H2 ZF 958 980
ENSP00000379370 C2H2 ZF 370 392
ENSP00000379370 C2H2 ZF 398 420
ENSP00000379370 C2H2 ZF 426 448
ENSP00000379370 C2H2 ZF 454 476
ENSP00000379370 C2H2 ZF 482 504
ENSP00000379370 C2H2 ZF 510 532
ENSP00000379370 C2H2 ZF 538 560
ENSP00000379370 C2H2 ZF 566 588
ENSP00000379370 C2H2 ZF 594 616
ENSP00000379370 C2H2 ZF 622 644
ENSP00000379370 C2H2 ZF 650 672
ENSP00000379370 C2H2 ZF 678 700
ENSP00000379370 C2H2 ZF 706 728
ENSP00000379370 C2H2 ZF 734 756
ENSP00000379370 C2H2 ZF 762 784
ENSP00000379370 C2H2 ZF 790 812
ENSP00000379370 C2H2 ZF 818 840
ENSP00000379370 C2H2 ZF 846 868
ENSP00000379370 C2H2 ZF 874 896
ENSP00000379370 C2H2 ZF 902 924
ENSP00000379370 C2H2 ZF 930 952
ENSP00000379370 C2H2 ZF 958 980

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

25 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSNLEG00000005974 Nomascus leucogenys ENSNLEG00000005974 I 0.825
ZNF197 Callithrix jacchus ENSCJAG00000001817 I 0.824
ENSPPYG00000013958 Pongo abelii ENSPPYG00000013958 I 0.823
ENSAMEG00000004769 Ailuropoda melanoleuca ENSAMEG00000004769 I 0.822
ENSPANG00000008111 Papio anubis ENSPANG00000008111 I 0.822
ENSMPUG00000002775 Mustela putorius furo ENSMPUG00000002775 I 0.822
ZNF197 Macaca mulatta ENSMMUG00000017585 I 0.822
ENSP00000345809 Macaca fascicularis ENSP00000345809 I 0.822
ENSCSAG00000016621 Chlorocebus sabaeus ENSCSAG00000016621 I 0.822
ZNF197 Vicugna pacos ENSVPAG00000006930 I 0.821
ZNF197 Pteropus vampyrus ENSPVAG00000013486 I 0.821
ZNF197 Dasypus novemcinctus ENSDNOG00000034353 I 0.821
ZNF197 Sus scrofa ENSSSCG00000011304 I 0.820
ZNF197 Choloepus hoffmanni ENSCHOG00000013986 I 0.820
ZNF197 Felis catus ENSFCAG00000021993 I 0.820
ZNF197 Otolemur garnettii ENSOGAG00000028821 I 0.820
ZNF197 Bos taurus ENSBTAG00000037803 I 0.813
ZNF197 Tursiops truncatus ENSTTRG00000006738 I 0.812
ENSOARG00000004589 Ovis aries ENSOARG00000004589 I 0.812
ZNF197 Procavia capensis ENSPCAG00000009444 I 0.807
ZNF197 Ochotona princeps ENSOPRG00000010881 I 0.784
ENSSTOG00000022902 Ictidomys tridecemlineatus ENSSTOG00000022902 I 0.784
ZNF197 Equus caballus ENSECAG00000011611 I 0.782
ZNF197 Echinops telfairi ENSETEG00000015360 I 0.777