ZNF396 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000186496 T095250_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables protein heterodimerization activity; protein homodimerization activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF396
M04611_2.00		 Homo sapiens
VTTTCGKACAB
VTGTMCGAAAB		 SELEX
Yin et al.(2017)
ZNF396_FL_HT-SELEX		 (Direct) (Direct)
ZNF396
M04612_2.00		 Homo sapiens
MTGTCCDAAAD
HTTTHGGACAK		 SELEX
Yin et al.(2017)
ZNF396_FL_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000302310 C2H2 ZF 251 273
ENSP00000302310 C2H2 ZF 279 301
ENSP00000466500 C2H2 ZF 251 273
ENSP00000466500 C2H2 ZF 279 301
ENSP00000466500 C2H2 ZF 307 329

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

6 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZNF396 Dasypus novemcinctus ENSDNOG00000041114 I 0.823
ZNF396 Gorilla gorilla ENSGGOG00000023692 I 0.813
ZNF396 Pan troglodytes ENSPTRG00000009970 N 0.808
ZNF396 Microcebus murinus ENSMICG00000017080 N 0.791
ZNF396 Tursiops truncatus ENSTTRG00000006748 I 0.784
ZNF396 Sus scrofa ENSSSCG00000030018 I 0.761