ZNF177 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000188629 T095269_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Located in blood microparticle. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF177
M04615_2.00		 Homo sapiens
BTYGRTCKMRNKKNNVAGTCATD
HATGACTBNNMMNYKMGAYCRAV		 SELEX
Yin et al.(2017)
ZNF177_eDBD_HT-SELEX		 (Direct) (Direct)
ZNF177
M04616_2.00		 Homo sapiens
BTNGATCTARVKKNVMAGTCATD
HATGACTKBNMMBYTAGATCNAV		 SELEX
Yin et al.(2017)
ZNF177_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000341497 C2H2 ZF 124 146
ENSP00000341497 C2H2 ZF 152 174
ENSP00000341497 C2H2 ZF 180 202
ENSP00000341497 C2H2 ZF 208 230
ENSP00000341497 C2H2 ZF 236 258
ENSP00000341497 C2H2 ZF 264 286
ENSP00000341497 C2H2 ZF 292 314
ENSP00000468531 C2H2 ZF 136 170
ENSP00000468531 C2H2 ZF 179 197
ENSP00000468531 C2H2 ZF 284 306
ENSP00000468531 C2H2 ZF 312 334
ENSP00000468531 C2H2 ZF 340 362
ENSP00000468531 C2H2 ZF 368 390
ENSP00000468531 C2H2 ZF 396 418
ENSP00000468531 C2H2 ZF 424 446
ENSP00000468531 C2H2 ZF 452 474

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

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15 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action