ZNF431 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000196705 T095316_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein may negatively regulate transcription of target genes, including the hedgehog signaling pathway receptor patched 1, by interacting with histone deacetylases. Mutations in this gene may be associated with non-syndromic facial clefting in human patients. [provided by RefSeq, Jul 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF431
M07711_2.00
Homo sapiens
BNRNCWKCYAGCCYB

VRGGCTRGMWGNYNV
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF431.ChIP-seq.ReprocessedData
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000308578 C2H2 ZF 204 226
ENSP00000308578 C2H2 ZF 232 254
ENSP00000308578 C2H2 ZF 260 282
ENSP00000308578 C2H2 ZF 288 310
ENSP00000308578 C2H2 ZF 316 338
ENSP00000308578 C2H2 ZF 344 366
ENSP00000308578 C2H2 ZF 372 394
ENSP00000308578 C2H2 ZF 400 422
ENSP00000308578 C2H2 ZF 428 450
ENSP00000308578 C2H2 ZF 456 478
ENSP00000308578 C2H2 ZF 484 506
ENSP00000308578 C2H2 ZF 512 534
ENSP00000308578 C2H2 ZF 540 557
ENSP00000471876 C2H2 ZF 244 266
ENSP00000471876 C2H2 ZF 272 294
ENSP00000471876 C2H2 ZF 300 322

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

4 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ZNF431 Pan troglodytes ENSPTRG00000019216 I 0.824
ENSCSAG00000004993 Chlorocebus sabaeus ENSCSAG00000004993 I 0.820
ENSPANG00000017037 Papio anubis ENSPANG00000017037 I 0.817
ENSCJAG00000013721 Callithrix jacchus ENSCJAG00000013721 I 0.791