ZNF398 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000197024 T095328_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the Kruppel family of C2H2-type zinc-finger transcription factor proteins. The encoded protein acts as a transcriptional activator. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described, but their full length sequence has not been determined. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF398
M07716_2.00		 Homo sapiens
CTSYYTCYYTCCCH
DGGGARRGARRSAG		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF398.ChIP-seq.ReprocessedData		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000389972 C2H2 ZF 172 193
ENSP00000389972 C2H2 ZF 228 249
ENSP00000389972 C2H2 ZF 256 278
ENSP00000389972 C2H2 ZF 284 306
ENSP00000389972 C2H2 ZF 312 334
ENSP00000389972 C2H2 ZF 340 362
ENSP00000389972 C2H2 ZF 368 390
ENSP00000389972 C2H2 ZF 396 419
ENSP00000418564 C2H2 ZF 172 193
ENSP00000418564 C2H2 ZF 228 249
ENSP00000418564 C2H2 ZF 256 278
ENSP00000418564 C2H2 ZF 284 306
ENSP00000418564 C2H2 ZF 312 334
ENSP00000418564 C2H2 ZF 340 362
ENSP00000418564 C2H2 ZF 368 390
ENSP00000418564 C2H2 ZF 396 419
ENSP00000419391 C2H2 ZF 172 193
ENSP00000419391 C2H2 ZF 228 249
ENSP00000419391 C2H2 ZF 256 278
ENSP00000419391 C2H2 ZF 284 306
ENSP00000419391 C2H2 ZF 312 334
ENSP00000419391 C2H2 ZF 340 362
ENSP00000419391 C2H2 ZF 368 390
ENSP00000419391 C2H2 ZF 396 419
ENSP00000420418 C2H2 ZF 343 364
ENSP00000420418 C2H2 ZF 399 420
ENSP00000420418 C2H2 ZF 427 449
ENSP00000420418 C2H2 ZF 455 477
ENSP00000420418 C2H2 ZF 483 505
ENSP00000420418 C2H2 ZF 511 533
ENSP00000420418 C2H2 ZF 539 561
ENSP00000420418 C2H2 ZF 567 590

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

25 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSPANG00000015944 Papio anubis ENSPANG00000015944 I 0.827
ZNF398 Gorilla gorilla ENSGGOG00000005812 I 0.827
ENSPPYG00000018150 Pongo abelii ENSPPYG00000018150 I 0.827
ZNF398 Pan troglodytes ENSPTRG00000023917 I 0.827
ENSP00000338984 Macaca fascicularis ENSP00000338984 I 0.827
ENSNLEG00000003700 Nomascus leucogenys ENSNLEG00000003700 I 0.827
ENSCSAG00000007015 Chlorocebus sabaeus ENSCSAG00000007015 I 0.827
ZNF398 Callithrix jacchus ENSCJAG00000010213 I 0.827
ZNF398 Otolemur garnettii ENSOGAG00000016740 I 0.825
ZNF398 Oryctolagus cuniculus ENSOCUG00000008416 I 0.825
ZNF398 Ochotona princeps ENSOPRG00000010531 I 0.822
ENSMICG00000016618 Microcebus murinus ENSMICG00000016618 I 0.821
ZNF398 Dasypus novemcinctus ENSDNOG00000038814 I 0.821
ZNF398 Canis familiaris ENSCAFG00000004429 I 0.820
ENSTSYG00000002784 Tarsius syrichta ENSTSYG00000002784 I 0.820
ENSMPUG00000006622 Mustela putorius furo ENSMPUG00000006622 I 0.813
ENSSTOG00000013384 Ictidomys tridecemlineatus ENSSTOG00000013384 I 0.813
Zfp398 Rattus norvegicus ENSRNOG00000006703 I 0.804
ZNF398 Myotis lucifugus ENSMLUG00000007451 I 0.804
Myotis_brandtii_ZNF398_10025637 Myotis brandtii Myotis_brandtii_ZNF398_10025637 I 0.804
Zfp398 Mus musculus ENSMUSG00000062519 I 0.801
ZNF398 Choloepus hoffmanni ENSCHOG00000007407 I 0.793
ZNF398 Bos taurus ENSBTAG00000020445 I 0.786
ZNF398 Pteropus vampyrus ENSPVAG00000010865 I 0.769