ZNF460 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000197714 T095354_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Zinc finger proteins, such as ZNF272, interact with nucleic acids and have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, May 2004]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF460
M04627_2.00		 Homo sapiens
CAACGCCCCCCGN
NCGGGGGGCGTTG		 SELEX
Yin et al.(2017)
ZNF460_eDBD_HT-SELEX		 (Direct) (Direct)
ZNF460
M04628_2.00		 Homo sapiens
NNMCBCCCCCCVN
NBGGGGGGVGKNN		 SELEX
Yin et al.(2017)
ZNF460_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
ZNF460
M07727_2.00		 Homo sapiens
SSCCDCCKCCCS
SGGGMGGHGGSS		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF460.RCADE.ReprocessedData		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000353491 C2H2 ZF 196 218
ENSP00000353491 C2H2 ZF 224 246
ENSP00000353491 C2H2 ZF 252 274
ENSP00000353491 C2H2 ZF 280 302
ENSP00000353491 C2H2 ZF 308 330
ENSP00000353491 C2H2 ZF 336 358
ENSP00000353491 C2H2 ZF 364 386
ENSP00000353491 C2H2 ZF 392 414
ENSP00000353491 C2H2 ZF 420 442
ENSP00000353491 C2H2 ZF 448 470
ENSP00000353491 C2H2 ZF 476 498
ENSP00000446167 C2H2 ZF 155 177
ENSP00000446167 C2H2 ZF 183 205
ENSP00000446167 C2H2 ZF 211 233
ENSP00000446167 C2H2 ZF 239 261
ENSP00000446167 C2H2 ZF 267 289
ENSP00000446167 C2H2 ZF 295 317
ENSP00000446167 C2H2 ZF 323 345
ENSP00000446167 C2H2 ZF 351 373
ENSP00000446167 C2H2 ZF 379 401
ENSP00000446167 C2H2 ZF 407 429
ENSP00000446167 C2H2 ZF 435 457

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

9 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZNF460 Pan troglodytes ENSPTRG00000011548 I 0.827
ENSNLEG00000010925 Nomascus leucogenys ENSNLEG00000010925 I 0.827
ENSP00000353491 Macaca fascicularis ENSP00000353491 I 0.824
ZNF460 Macaca mulatta ENSMMUG00000019285 I 0.824
ENSPANG00000019732 Papio anubis ENSPANG00000019732 I 0.824
ENSCSAG00000001646 Chlorocebus sabaeus ENSCSAG00000001646 I 0.820
ZNF460 Callithrix jacchus ENSCJAG00000000026 I 0.807
ENSPPYG00000010460 Pongo abelii ENSPPYG00000010460 I 0.760