ZNF81 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000197779 T095355_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability. [provided by RefSeq, Jul 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF81
M07728_2.00
Homo sapiens
TYBNDRSTRGTBBBACCA

TGGTVVVACYASYHNVRA
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF81.RCADE.OriginalMapping
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000341151 C2H2 ZF 330 352
ENSP00000341151 C2H2 ZF 358 380
ENSP00000341151 C2H2 ZF 386 408
ENSP00000341151 C2H2 ZF 414 436
ENSP00000341151 C2H2 ZF 442 464
ENSP00000341151 C2H2 ZF 470 492
ENSP00000341151 C2H2 ZF 498 520
ENSP00000341151 C2H2 ZF 526 548
ENSP00000341151 C2H2 ZF 554 576
ENSP00000341151 C2H2 ZF 582 604
ENSP00000341151 C2H2 ZF 610 632
ENSP00000341151 C2H2 ZF 638 660
ENSP00000366153 C2H2 ZF 330 352
ENSP00000366153 C2H2 ZF 358 380
ENSP00000366153 C2H2 ZF 386 408
ENSP00000366153 C2H2 ZF 414 436
ENSP00000366153 C2H2 ZF 442 464
ENSP00000366153 C2H2 ZF 470 492
ENSP00000366153 C2H2 ZF 498 520
ENSP00000366153 C2H2 ZF 526 548
ENSP00000366153 C2H2 ZF 554 576
ENSP00000366153 C2H2 ZF 582 604
ENSP00000366153 C2H2 ZF 610 632
ENSP00000366153 C2H2 ZF 638 660

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

32 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSNLEG00000003479 Nomascus leucogenys ENSNLEG00000003479 I 0.827
ENSPANG00000008099 Papio anubis ENSPANG00000008099 I 0.827
ZNF81 Gorilla gorilla ENSGGOG00000010830 I 0.827
ZNF81 Macaca mulatta ENSMMUG00000014066 I 0.826
ENSP00000366153 Macaca fascicularis ENSP00000366153 I 0.826
ZNF81 Pan troglodytes ENSPTRG00000023331 I 0.824
ENSCSAG00000013582 Chlorocebus sabaeus ENSCSAG00000013582 I 0.823
ZNF81 Callithrix jacchus ENSCJAG00000015620 I 0.815
ZNF81 Tupaia belangeri ENSTBEG00000001263 I 0.813
ENSSTOG00000008624 Ictidomys tridecemlineatus ENSSTOG00000008624 I 0.812
ZNF81 Tursiops truncatus ENSTTRG00000004239 I 0.808
ZNF81 Sus scrofa ENSSSCG00000012283 I 0.808
ENSTSYG00000008231 Tarsius syrichta ENSTSYG00000008231 I 0.808
ZNF81 Felis catus ENSFCAG00000022818 I 0.807
ZNF81 Canis familiaris ENSCAFG00000015170 I 0.806
ENSOARG00000012586 Ovis aries ENSOARG00000012586 I 0.805
ENSAMEG00000012840 Ailuropoda melanoleuca ENSAMEG00000012840 I 0.804
ZNF81 Myotis lucifugus ENSMLUG00000011734 I 0.800
ZNF81 Pteropus vampyrus ENSPVAG00000005467 I 0.798
ZNF81 Equus caballus ENSECAG00000019179 I 0.798
ENSMPUG00000013422 Mustela putorius furo ENSMPUG00000013422 I 0.795
ZNF81 Bos taurus ENSBTAG00000005866 I 0.794
ENSBTAP00000029728-D23 Bos grunniens ENSBTAP00000029728-D23 I 0.794
ZNF81 Vicugna pacos ENSVPAG00000002762 I 0.793
ZNF81 Sorex araneus ENSSARG00000012388 I 0.792
ZNF81 Oryctolagus cuniculus ENSOCUG00000029071 I 0.789
ZNF81 Otolemur garnettii ENSOGAG00000014983 I 0.783
ZNF81 Erinaceus europaeus ENSEEUG00000012650 I 0.779
ZNF81 Dasypus novemcinctus ENSDNOG00000041183 I 0.778
ZNF81 Ochotona princeps ENSOPRG00000003198 I 0.762
ENSPPYG00000020302 Pongo abelii ENSPPYG00000020302 I 0.757