ZFP57 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000204644 T095416_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).[provided by RefSeq, Sep 2009]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZFP57
M07756_2.00		 Homo sapiens
GCGGCA
TGCCGC		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZFP57.MEME.OriginalMapping		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000366078 C2H2 ZF 91 113
ENSP00000366078 C2H2 ZF 120 141
ENSP00000366078 C2H2 ZF 147 169
ENSP00000366078 C2H2 ZF 175 197
ENSP00000366078 C2H2 ZF 300 322
ENSP00000366078 C2H2 ZF 329 350
ENSP00000366078 C2H2 ZF 356 377
ENSP00000366080 C2H2 ZF 155 177
ENSP00000366080 C2H2 ZF 184 205
ENSP00000366080 C2H2 ZF 211 233
ENSP00000366080 C2H2 ZF 239 261
ENSP00000366080 C2H2 ZF 364 386
ENSP00000366080 C2H2 ZF 393 414
ENSP00000366080 C2H2 ZF 420 441
ENSP00000418259 C2H2 ZF 175 197
ENSP00000418259 C2H2 ZF 204 225
ENSP00000418259 C2H2 ZF 231 253
ENSP00000418259 C2H2 ZF 259 281
ENSP00000418259 C2H2 ZF 384 406
ENSP00000418259 C2H2 ZF 413 434
ENSP00000418259 C2H2 ZF 440 461

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

6 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZFP57 Pan troglodytes ENSPTRG00000017904 I 0.826
ZFP57 Gorilla gorilla ENSGGOG00000016915 I 0.823
ENSNLEG00000004723 Nomascus leucogenys ENSNLEG00000004723 I 0.819
ENSP00000418259 Macaca fascicularis ENSP00000418259 I 0.803
ENSPPYG00000016397 Pongo abelii ENSPPYG00000016397 I 0.787