ZNF425 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000204947 T095420_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription, DNA-templated. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF425
M07758_2.00		 Homo sapiens
SGCCCTC
GAGGGCS		 ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF425.MEME.OriginalMapping		 (Direct) (Direct)
ZNF425
M10320_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ZNF425_04		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000367300 C2H2 ZF 190 212
ENSP00000367300 C2H2 ZF 246 268
ENSP00000367300 C2H2 ZF 274 296
ENSP00000367300 C2H2 ZF 302 324
ENSP00000367300 C2H2 ZF 330 352
ENSP00000367300 C2H2 ZF 358 380
ENSP00000367300 C2H2 ZF 386 408
ENSP00000367300 C2H2 ZF 414 436
ENSP00000367300 C2H2 ZF 442 464
ENSP00000367300 C2H2 ZF 470 492
ENSP00000367300 C2H2 ZF 498 520
ENSP00000367300 C2H2 ZF 526 548
ENSP00000367300 C2H2 ZF 554 576
ENSP00000367300 C2H2 ZF 582 604
ENSP00000367300 C2H2 ZF 610 632
ENSP00000367300 C2H2 ZF 638 660
ENSP00000367300 C2H2 ZF 666 688
ENSP00000367300 C2H2 ZF 694 716
ENSP00000367300 C2H2 ZF 722 744

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

8 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action