ZIM2 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000269699 T095496_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
In human, ZIM2 and PEG3 (GeneID:5178) are two distinct genes that share a set of 5' exons and have a common promoter, and both genes are paternally expressed. Alternative splicing events connect the shared exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. This is in contrast to mouse and cow, where ZIM2 and PEG3 genes do not share exons in common, and the imprinting status of ZIM2 is also not conserved amongst mammals. Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene. [provided by RefSeq, Oct 2010]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZIM2
M07779_2.00
Homo sapiens
YCNBSYBSCYTYYYCHBCCVGCCYGKGGYY

RRCCMCRGGCBGGVDGRRRARGSVRSVNGR
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZIM2.ChIP-seq.ReprocessedData
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000468984 C2H2 ZF 329 350
ENSP00000468984 C2H2 ZF 356 378
ENSP00000468984 C2H2 ZF 412 434
ENSP00000468984 C2H2 ZF 466 488
ENSP00000468984 C2H2 ZF 494 516
ENSP00000470326 C2H2 ZF 329 350
ENSP00000470326 C2H2 ZF 356 378
ENSP00000470326 C2H2 ZF 412 434
ENSP00000470326 C2H2 ZF 466 488
ENSP00000470326 C2H2 ZF 494 516
ENSP00000472306 C2H2 ZF 329 350
ENSP00000472306 C2H2 ZF 356 378
ENSP00000472306 C2H2 ZF 412 434
ENSP00000472306 C2H2 ZF 466 488
ENSP00000472306 C2H2 ZF 494 516
ENSP00000486502 C2H2 ZF 329 350
ENSP00000486502 C2H2 ZF 356 378
ENSP00000486502 C2H2 ZF 412 434
ENSP00000486502 C2H2 ZF 466 488
ENSP00000486502 C2H2 ZF 494 516

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

3 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
PEG3 Macaca mulatta ENSMMUG00000017852 I 0.768
ENSCSAG00000001663 Chlorocebus sabaeus ENSCSAG00000001663 I 0.768