ZNF8 (Homo sapiens)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSG00000278129 T095503_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within BMP signaling pathway. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
ZNF8
M07781_2.00
Homo sapiens
RYRTACCRCWKY

RMWGYGGTAYRY
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF8.RCADE.OriginalMapping
(Direct) (Direct)
ZNF8
M08401_2.00
Homo sapiens
NNBVYGGTAYGYCHHNDH

DHNDDGRCRTACCRBVNN
ChIP-seq
Schmitges et al.(2016)
P17098_1-6.RCADE
(Direct) (Direct)
ZNF8
M08961_2.00
Homo sapiens
TCCATTGTATGGATRTACCACA

TGTGGTAYATCCATACAATGGA
Misc
Kulakovskiy et al.(2013)
ZNF8_HUMAN.H11MO.0.C
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000477716 C2H2 ZF 257 279
ENSP00000477716 C2H2 ZF 285 307
ENSP00000477716 C2H2 ZF 313 335
ENSP00000477716 C2H2 ZF 341 363
ENSP00000477716 C2H2 ZF 369 391
ENSP00000477716 C2H2 ZF 397 419

Links

Other C2H2 ZF family TFs
Other Homo sapiens TFs

Invalid Input OrderBy

22 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action