CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ZNF8
(
Homo sapiens
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSG00000278129
T095503_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within BMP signaling pathway. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ZNF8
M07781_2.00
Homo sapiens
RYRTACCRCWKY
RMWGYGGTAYRY
ChIP-seq+ChIP-exo
Barazandeh et al.(2018)
ZNF8.RCADE.OriginalMapping
(Direct)
(Direct)
ZNF8
M08401_2.00
Homo sapiens
NNBVYGGTAYGYCHHNDH
DHNDDGRCRTACCRBVNN
ChIP-seq
Schmitges et al.(2016)
P17098_1-6.RCADE
(Direct)
(Direct)
ZNF8
M08961_2.00
Homo sapiens
TCCATTGTATGGATRTACCACA
TGTGGTAYATCCATACAATGGA
Misc
Kulakovskiy et al.(2013)
ZNF8_HUMAN.H11MO.0.C
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSP00000477716
C2H2 ZF
257
279
YKCTDCGKSFNHNAHLTVHKRIH
ENSP00000477716
C2H2 ZF
285
307
YMCKECGKAFSQNSSLVQHERIH
ENSP00000477716
C2H2 ZF
313
335
YKCAECGKSFCHSTHLTVHRRIH
ENSP00000477716
C2H2 ZF
341
363
YECQDCGRAFNQNSSLGRHKRTH
ENSP00000477716
C2H2 ZF
369
391
YTCSVCGKSFSRTTCLFLHLRTH
ENSP00000477716
C2H2 ZF
397
419
YECNHCGKGFRHSSSLAQHQRKH
Links
Other
C2H2 ZF
family TFs
Other
Homo sapiens
TFs
22 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy