Hivep2 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000015501 T100998_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within signal transduction and transcription, DNA-templated. Predicted to be located in nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; hepatic primordium; and urinary system. Used to study intellectual disability and schizophrenia. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 43. Orthologous to human HIVEP2 (HIVEP zinc finger 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HIVEP2
M10101_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MIBP1_Q6 		0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000015645 C2H2 ZF 189 211
ENSMUSP00000015645 C2H2 ZF 217 239
ENSMUSP00000015645 C2H2 ZF 1783 1805
ENSMUSP00000015645 C2H2 ZF 1811 1835
ENSMUSP00000140150 C2H2 ZF 189 211
ENSMUSP00000140150 C2H2 ZF 217 239
ENSMUSP00000140150 C2H2 ZF 1783 1805
ENSMUSP00000140150 C2H2 ZF 1811 1835
ENSMUSP00000140180 C2H2 ZF 189 211
ENSMUSP00000140180 C2H2 ZF 217 239
ENSMUSP00000140290 C2H2 ZF 189 211
ENSMUSP00000140290 C2H2 ZF 217 239
ENSMUSP00000140290 C2H2 ZF 1783 1805
ENSMUSP00000140290 C2H2 ZF 1811 1835

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

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229 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action