E4f1 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000024137 T101043_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the GLI-Kruppel zinc finger family. The encoded protein is likely to be multi-functional, with both adenovirus E1A-regulated transcription factor and ubiquitin E3 ligase activities, including roles in cell cycle regulation and the ubiquitination of p53. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
E4f1
M10339_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$PHIAP3_03
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
E4F1
M10255_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$E4F1_Q6_01
0.817 0.971
E4F1
M10256_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$E4F1_Q6
0.817 0.971
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000062344 C2H2 ZF 193 215
ENSMUSP00000062344 C2H2 ZF 221 243
ENSMUSP00000062344 C2H2 ZF 249 270
ENSMUSP00000062344 C2H2 ZF 433 455
ENSMUSP00000062344 C2H2 ZF 461 483
ENSMUSP00000062344 C2H2 ZF 489 511
ENSMUSP00000062344 C2H2 ZF 517 539
ENSMUSP00000062344 C2H2 ZF 545 567
ENSMUSP00000062344 C2H2 ZF 573 594

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

30 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
E4f1 Rattus norvegicus ENSRNOG00000009224 I 0.826
E4F1 Oryctolagus cuniculus ENSOCUG00000025484 I 0.825
E4F1 Microcebus murinus ENSMICG00000005892 I 0.825
E4F1 Otolemur garnettii ENSOGAG00000006594 I 0.824
E4F1 Equus caballus ENSECAG00000008036 I 0.824
E4F1 Bos taurus ENSBTAG00000009961 I 0.824
ENSOARG00000017910 Ovis aries ENSOARG00000017910 I 0.824
E4F1 Callithrix jacchus ENSCJAG00000015000 I 0.824
ENSP00000301727-D1 Bos grunniens ENSP00000301727-D1 I 0.824
E4F1 Tursiops truncatus ENSTTRG00000008208 I 0.824
ENSAMEG00000017837 Ailuropoda melanoleuca ENSAMEG00000017837 I 0.822
E4F1 Sus scrofa ENSSSCG00000008047 I 0.822
E4F1 Pteropus vampyrus ENSPVAG00000005098 I 0.822
ENSMPUG00000015378 Mustela putorius furo ENSMPUG00000015378 I 0.821
E4F1 Cavia porcellus ENSCPOG00000002052 I 0.821
E4F1 Ochotona princeps ENSOPRG00000002573 I 0.819
E4F1 Loxodonta africana ENSLAFG00000000725 I 0.818
E4F1 Homo sapiens ENSG00000167967 D 0.817
ENSCSAG00000010850 Chlorocebus sabaeus ENSCSAG00000010850 I 0.817
E4F1 Macaca mulatta ENSMMUG00000019235 I 0.817
ENSPANG00000017016 Papio anubis ENSPANG00000017016 I 0.817
ENSP00000301727 Macaca fascicularis ENSP00000301727 I 0.817
ENSNLEG00000009261 Nomascus leucogenys ENSNLEG00000009261 I 0.817
E4F1 Gorilla gorilla ENSGGOG00000014241 I 0.817
Myotis_brandtii_E4f1_10005619 Myotis brandtii Myotis_brandtii_E4f1_10005619 I 0.814
E4F1 Myotis lucifugus ENSMLUG00000016786 I 0.814
E4F1 Dasypus novemcinctus ENSDNOG00000016503 I 0.812
E4f1 Dipodomys ordii ENSDORG00000001751 I 0.811
E4F1 Procavia capensis ENSPCAG00000004337 I 0.810
ENSSTOG00000013171 Ictidomys tridecemlineatus ENSSTOG00000013171 I 0.806