Ovol1 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000024922 T101051_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including negative regulation of stem cell proliferation; negative regulation of transcription by RNA polymerase II; and regulation of meiotic cell cycle. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Orthologous to human OVOL1 (ovo like transcriptional repressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Ovol1
M08974_2.00		 Mus musculus
WCMGTTACM
KGTAACKGW		 Misc
Kulakovskiy et al.(2013)
OVOL1_MOUSE.H11MO.0.C		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
OVOL1
M04556_2.00 		Homo sapiens
NDDACCGTTAYNYN
NRNRTAACGGTHHN		 SELEX
Yin et al.(2017)
OVOL1_FL_HT-SELEX 		0.819 0.942
OVOL1
M08919_2.00 		Homo sapiens
WCMGTTACM
KGTAACKGW		 Misc
Kulakovskiy et al.(2013)
OVOL1_HUMAN.H11MO.0.C 		0.819 0.942
OVOL1
M04557_2.00 		Homo sapiens
NDDACCGTTAYNYN
NRNRTAACGGTHHN		 SELEX
Yin et al.(2017)
OVOL1_FL_Methyl-HT-SELEX 		0.819 0.942
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000025861 C2H2 ZF 118 140
ENSMUSP00000025861 C2H2 ZF 146 168
ENSMUSP00000025861 C2H2 ZF 174 197

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

Invalid Input OrderBy

35 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action