Mzf1 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000030380 T101092_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Is expressed in bladder; male associated reproductive structure; testis; and urethra of male. Orthologous to human MZF1 (myeloid zinc finger 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mzf1
M00772_2.00		 Mus musculus
NRATCCCCHH
DDGGGGATYN		 PBM
Weirauch et al.(2013)
pTH3984		 (Direct) (Direct)
Mzf1
M00773_2.00		 Mus musculus
RATCCCCH
DGGGGATY		 PBM
Weirauch et al.(2013)
pTH3991		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MZF1
M02663_2.00 		Homo sapiens
TCCCCN
NGGGGA		 SELEX
Mathelier et al.(2014)
MA0056.1 		0.821 0.970
MZF1
M02664_2.00 		Homo sapiens
BYHCCCMTMV
BKAKGGGDRV		 SELEX
Mathelier et al.(2014)
MA0057.1 		0.821 0.970
MZF1
M08236_2.00 		Homo sapiens
CCATTTT
AAAATGG		 ChIP-seq
Najafabadi et al.(2015b)
MZF1 		0.821 0.970
MZF1
M08286_2.00 		Homo sapiens
HAARATGGCKSCYNN
NNRGSMGCCATYTTD		 ChIP-seq
Schmitges et al.(2016)
P28698.MEME 		0.821 0.970
MZF1
M08863_2.00 		Homo sapiens
BYNMWTCCCYHYB
VRDRGGGAWKNRV		 Misc
Kulakovskiy et al.(2013)
MZF1_HUMAN.H11MO.0.B 		0.821 0.970
MZF1
M10133_2.00 		Homo sapiens
TCCCCNHN
NDNGGGGA		 Transfac
Matys et al.(2006)
V$MZF1_01 		0.821 0.970
MZF1
M10134_2.00 		Homo sapiens
KWBCCCCTMVHHM
KDDBKAGGGGVAM		 Transfac
Matys et al.(2006)
V$MZF1_02 		0.821 0.970
MZF1
M10135_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MZF1_Q5_01 		0.821 0.970
MZF1
M10136_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$MZF1_Q5 		0.821 0.970
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00772_2.00 C2H2 ZF 17 38
M00772_2.00 C2H2 ZF 44 66
M00772_2.00 C2H2 ZF 72 94
M00773_2.00 C2H2 ZF 17 38
M00773_2.00 C2H2 ZF 44 66
M00773_2.00 C2H2 ZF 72 94
M00773_2.00 C2H2 ZF 100 122
M00773_2.00 C2H2 ZF 145 167
M00773_2.00 C2H2 ZF 173 195
M00773_2.00 C2H2 ZF 201 223
M00773_2.00 C2H2 ZF 229 251
M00773_2.00 C2H2 ZF 257 279
M00773_2.00 C2H2 ZF 285 307
M00773_2.00 C2H2 ZF 313 335
M00773_2.00 C2H2 ZF 341 363
M00773_2.00 C2H2 ZF 369 391

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000138271 C2H2 ZF 437 458
ENSMUSP00000138271 C2H2 ZF 464 486
ENSMUSP00000138271 C2H2 ZF 492 514
ENSMUSP00000138271 C2H2 ZF 520 542
ENSMUSP00000138271 C2H2 ZF 565 587
ENSMUSP00000138271 C2H2 ZF 593 615
ENSMUSP00000138271 C2H2 ZF 621 643
ENSMUSP00000138271 C2H2 ZF 649 671
ENSMUSP00000138271 C2H2 ZF 677 699
ENSMUSP00000138271 C2H2 ZF 705 727
ENSMUSP00000138271 C2H2 ZF 733 755
ENSMUSP00000138271 C2H2 ZF 761 783
ENSMUSP00000138271 C2H2 ZF 789 811
ENSMUSP00000138387 C2H2 ZF 358 379
ENSMUSP00000138387 C2H2 ZF 385 407
ENSMUSP00000138387 C2H2 ZF 413 435
ENSMUSP00000138387 C2H2 ZF 441 463
ENSMUSP00000138387 C2H2 ZF 486 508
ENSMUSP00000138387 C2H2 ZF 514 536
ENSMUSP00000138387 C2H2 ZF 542 564
ENSMUSP00000138387 C2H2 ZF 598 620
ENSMUSP00000138387 C2H2 ZF 654 676
ENSMUSP00000138387 C2H2 ZF 710 732

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

Invalid Input OrderBy

21 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action