Sall1 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000031665 T101105_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including negative regulation of ectoderm development; negative regulation of mesoderm development; and nephron epithelium morphogenesis. Acts upstream of or within several processes, including limb morphogenesis; nervous system development; and regulation of transcription by RNA polymerase II. Located in heterochromatin and nucleus. Part of NuRD complex. Is expressed in several structures, including autopod; central nervous system; embryo mesenchyme; metanephros; and sensory organ. Used to study Townes-Brocks syndrome. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome and middle lobe syndrome. Orthologous to human SALL1 (spalt like transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Sall1
M10342_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SALL1_04		 (Direct) (Direct)
Sall1
M10343_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SALL1_05		 (Direct) (Direct)
Sall1
M10344_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SALL1_06		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000034090 C2H2 ZF 450 472
ENSMUSP00000034090 C2H2 ZF 478 500
ENSMUSP00000034090 C2H2 ZF 733 755
ENSMUSP00000034090 C2H2 ZF 765 787
ENSMUSP00000034090 C2H2 ZF 1000 1022
ENSMUSP00000034090 C2H2 ZF 1028 1050
ENSMUSP00000034090 C2H2 ZF 1133 1155
ENSMUSP00000034090 C2H2 ZF 1161 1183

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

50 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SALL1 Sus scrofa ENSSSCG00000002836 I 0.827
ENSSTOG00000020885 Ictidomys tridecemlineatus ENSSTOG00000020885 I 0.827
SALL1 Taeniopygia guttata ENSTGUG00000007514 I 0.827
SALL1 Sorex araneus ENSSARG00000000661 I 0.827
SALL1 Pan troglodytes ENSPTRG00000008108 I 0.827
ENSMPUG00000003265 Mustela putorius furo ENSMPUG00000003265 I 0.827
SALL1 Oryctolagus cuniculus ENSOCUG00000004364 I 0.827
ENSPSIG00000008582 Pelodiscus sinensis ENSPSIG00000008582 I 0.827
Aan_R003881 Calypte anna Aan_R003881 I 0.827
Afo_R009175 Aptenodytes forsteri Afo_R009175 I 0.827
Gfo_R010713 Geospiza fortis Gfo_R010713 I 0.827
Pvit_15502 Pogona vitticeps Pvit_15502 I 0.827
Tal_R006196 Tyto alba Tal_R006196 I 0.827
ENSP00000251020 Macaca fascicularis ENSP00000251020 I 0.827
Cmyd_10020158 Chelonia mydas Cmyd_10020158 I 0.827
Alligator_sinensis_CCG006627.1 Alligator sinensis Alligator_sinensis_CCG006627.1 I 0.827
Brh_R007445 Buceros rhinoceros Brh_R007445 I 0.827
SALL1 Gorilla gorilla ENSGGOG00000000663 I 0.827
SALL1 Meleagris gallopavo ENSMGAG00000004704 I 0.827
ENSDORG00000004249 Dipodomys ordii ENSDORG00000004249 I 0.827
ENSFALG00000000074 Ficedula albicollis ENSFALG00000000074 I 0.827
SALL1 Equus caballus ENSECAG00000011334 I 0.827
SALL1 Echinops telfairi ENSETEG00000015150 I 0.827
ENSGALG00000003739 Gallus gallus ENSGALG00000003739 I 0.827
SALL1 Homo sapiens ENSG00000103449 I 0.827
SALL1 Callithrix jacchus ENSCJAG00000001740 I 0.827
ENSAMEG00000006817 Ailuropoda melanoleuca ENSAMEG00000006817 I 0.827
ENSAPLG00000003356 Anas platyrhynchos ENSAPLG00000003356 I 0.827
SALL1 Bos taurus ENSBTAG00000008544 I 0.827
SALL1 Erinaceus europaeus ENSEEUG00000002014 I 0.827
SALL1 Canis familiaris ENSCAFG00000009755 I 0.827
ENSBTAP00000011264-D1 Bos grunniens ENSBTAP00000011264-D1 I 0.826
SALL1 Dasypus novemcinctus ENSDNOG00000016413 I 0.826
ENSSHAG00000009477 Sarcophilus harrisii ENSSHAG00000009477 I 0.826
ENSMEUG00000012206 Macropus eugenii ENSMEUG00000012206 I 0.826
SALL1 Loxodonta africana ENSLAFG00000015251 I 0.826
SALL1 Monodelphis domestica ENSMODG00000013114 I 0.826
SALL1 Myotis lucifugus ENSMLUG00000015541 I 0.826
SALL1 Anolis carolinensis ENSACAG00000014399 I 0.824
ENSLACG00000003556 Latimeria chalumnae ENSLACG00000003556 I 0.823
ENSPPYG00000007345 Pongo abelii ENSPPYG00000007345 I 0.822
ENSGMOG00000006103 Gadus morhua ENSGMOG00000006103 I 0.815
ENSAMXG00000018599 Astyanax mexicanus ENSAMXG00000018599 I 0.812
sall1a Danio rerio ENSDARG00000074319 I 0.811
SALL1 Procavia capensis ENSPCAG00000008162 I 0.803
ENSCSAG00000005319 Chlorocebus sabaeus ENSCSAG00000005319 I 0.792
ENSAMXG00000017702 Astyanax mexicanus ENSAMXG00000017702 I 0.772
sall3.L Xenopus laevis XB-GENE-866033 I 0.771
SALL3 Echinops telfairi ENSETEG00000001481 I 0.769
Aan_R015320 Calypte anna Aan_R015320 I 0.766