Sall1 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000031665 T101105_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including negative regulation of ectoderm development; negative regulation of mesoderm development; and nephron epithelium morphogenesis. Acts upstream of or within several processes, including limb morphogenesis; nervous system development; and regulation of transcription by RNA polymerase II. Located in heterochromatin and nucleus. Part of NuRD complex. Is expressed in several structures, including autopod; central nervous system; embryo mesenchyme; metanephros; and sensory organ. Used to study Townes-Brocks syndrome. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome and middle lobe syndrome. Orthologous to human SALL1 (spalt like transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Sall1
M10342_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SALL1_04		 (Direct) (Direct)
Sall1
M10343_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SALL1_05		 (Direct) (Direct)
Sall1
M10344_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SALL1_06		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000034090 C2H2 ZF 450 472
ENSMUSP00000034090 C2H2 ZF 478 500
ENSMUSP00000034090 C2H2 ZF 733 755
ENSMUSP00000034090 C2H2 ZF 765 787
ENSMUSP00000034090 C2H2 ZF 1000 1022
ENSMUSP00000034090 C2H2 ZF 1028 1050
ENSMUSP00000034090 C2H2 ZF 1133 1155
ENSMUSP00000034090 C2H2 ZF 1161 1183

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

Invalid Input OrderBy

50 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action