Zbtb1 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000033454 T101111_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables protein homodimerization activity. Involved in positive regulation of T cell mediated immunity; positive regulation of lymphocyte differentiation; and thymus development. Acts upstream of or within B cell differentiation and T cell differentiation in thymus. Predicted to be located in centrosome; nuclear body; and nuclear membrane. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; cerebral cortex; female reproductive system; trigeminal ganglion; and urinary system. Orthologous to human ZBTB1 (zinc finger and BTB domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zbtb1
M00775_2.00		 Mus musculus
NHMMCGCRHN
NDYGCGKKDN		 PBM
Weirauch et al.(2013)
pTH2366		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00775_2.00 C2H2 ZF 334 355
M00775_2.00 C2H2 ZF 374 400
M00775_2.00 C2H2 ZF 406 428
M00775_2.00 C2H2 ZF 462 484
M00775_2.00 C2H2 ZF 486 509

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000041955 C2H2 ZF 534 555
ENSMUSP00000041955 C2H2 ZF 574 600
ENSMUSP00000041955 C2H2 ZF 606 628
ENSMUSP00000041955 C2H2 ZF 662 684
ENSMUSP00000041955 C2H2 ZF 686 709

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

Invalid Input OrderBy

40 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action