Prdm1 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000038151 T101145_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables histone deacetylase binding activity; promoter-specific chromatin binding activity; and sequence-specific DNA binding activity. Involved in regulation of NK T cell differentiation; regulation of extrathymic T cell differentiation; and regulation of natural killer cell differentiation. Acts upstream of or within several processes, including animal organ development; artery development; and regulation of B cell activation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; reproductive system; retina; and skin. Used to study systemic lupus erythematosus. Orthologous to human PRDM1 (PR/SET domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Prdm1
M08995_2.00		 Mus musculus
NNACTTTCHCTTYY
RRAAGDGAAAGTNN		 Misc
Kulakovskiy et al.(2013)
PRDM1_MOUSE.H11MO.0.A		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PRDM1
M02874_2.00 		Homo sapiens
NHACTTTCACTTTYN
NRAAAGTGAAAGTDN		 SELEX
Jolma et al.(2013)
PRDM1_1 		0.825 0.982
PRDM1
M02731_2.00 		Homo sapiens
YACTTTCACTTT
AAAGTGAAAGTR		 SELEX
Jolma et al.(2010)
PRDM1_dimer 		0.825 0.982
PRDM1
M04396_2.00 		Homo sapiens
NYACTTTCVCYN
NRGBGAAAGTRN		 SELEX
Yin et al.(2017)
PRDM1_eDBD_HT-SELEX 		0.825 0.982
PRDM1
M08083_2.00 		Homo sapiens
NHACTTTCHY
RDGAAAGTDN		 ChIP-seq
Mathelier et al.(2014)
MA0508.2 		0.825 0.982
PRDM1
M07845_2.00 		Homo sapiens
NHACTTTCHCTTHYN
NRDAAGDGAAAGTDN		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_PRDM1_Stanford 		0.825 0.982
PRDM1
M08191_2.00 		Homo sapiens
ACTTTCAC
GTGAAAGT		 ChIP-seq
Contrino et al.(2012)
Mv110 		0.825 0.982
PRDM1
M08192_2.00 		Homo sapiens
HRTCACTTT
AAAGTGAYD		 ChIP-seq
Contrino et al.(2012)
Mv112 		0.825 0.982
PRDM1
M08276_2.00 		Homo sapiens
HHNBYVCTTTCHCYY
RRGDGAAAGBRVNDD		 ChIP-seq
Schmitges et al.(2016)
O75626.MEME 		0.825 0.982
PRDM1
M08854_2.00 		Homo sapiens
NNACTTTCHCTTYY
RRAAGDGAAAGTNN		 Misc
Kulakovskiy et al.(2013)
PRDM1_HUMAN.H11MO.0.A 		0.825 0.982
PRDM1
M09500_2.00 		Homo sapiens
ACTTTCHCTKNN
NNMAGDGAAAGT		 Misc
Heinz et al.(2010)
Hela-PRDM1_GSE31477 		0.825 0.982
PRDM1
M10108_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BLIMP1_Q4 		0.825 0.982
PRDM1
M10109_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BLIMP1_Q6_01 		0.825 0.982
PRDM1
M10110_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$BLIMP1_Q6 		0.825 0.982
PRDM1
M10111_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PRDM1_03 		0.825 0.982
PRDM1
M04397_2.00 		Homo sapiens
NCACTTTCVCYN
NRGBGAAAGTGN		 SELEX
Yin et al.(2017)
PRDM1_eDBD_Methyl-HT-SELEX 		0.825 0.982
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000039248 C2H2 ZF 606 628
ENSMUSP00000039248 C2H2 ZF 634 656
ENSMUSP00000039248 C2H2 ZF 662 684
ENSMUSP00000039248 C2H2 ZF 690 712
ENSMUSP00000039248 C2H2 ZF 718 739
ENSMUSP00000101129 C2H2 ZF 573 595
ENSMUSP00000101129 C2H2 ZF 601 623
ENSMUSP00000101129 C2H2 ZF 629 651
ENSMUSP00000101129 C2H2 ZF 657 679
ENSMUSP00000101129 C2H2 ZF 685 706

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

Invalid Input OrderBy

43 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action