Ikzf5 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000040167 T101160_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of protein-containing complex. Is expressed in several structures, including eye; genitourinary system; gut; integumental system; and nervous system. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human IKZF5 (IKAROS family zinc finger 5). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Ikzf5
M10347_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IKZF5_02		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000035583 C2H2 ZF 82 104
ENSMUSP00000035583 C2H2 ZF 110 132
ENSMUSP00000035583 C2H2 ZF 138 161
ENSMUSP00000123530 C2H2 ZF 82 104
ENSMUSP00000139528 BED ZF 72 105

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

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68 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action