Zfp3 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000043602 T101183_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Is expressed in genitourinary system. Orthologous to human ZFP3 (ZFP3 zinc finger protein). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zfp3
M00782_2.00		 Mus musculus
NGTGYDCGYNN
NNRCGHRCACN		 PBM
Weirauch et al.(2013)
pTH3220		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00782_2.00 C2H2 ZF 16 38
M00782_2.00 C2H2 ZF 44 66
M00782_2.00 C2H2 ZF 72 94
M00782_2.00 C2H2 ZF 100 122
M00782_2.00 C2H2 ZF 128 150
M00782_2.00 C2H2 ZF 156 178
M00782_2.00 C2H2 ZF 184 206
M00782_2.00 C2H2 ZF 212 234
M00782_2.00 C2H2 ZF 240 257

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000054020 C2H2 ZF 136 158
ENSMUSP00000054020 C2H2 ZF 164 186
ENSMUSP00000054020 C2H2 ZF 192 214
ENSMUSP00000054020 C2H2 ZF 220 242
ENSMUSP00000054020 C2H2 ZF 248 270
ENSMUSP00000054020 C2H2 ZF 276 298
ENSMUSP00000054020 C2H2 ZF 304 326
ENSMUSP00000054020 C2H2 ZF 332 354
ENSMUSP00000054020 C2H2 ZF 360 377

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

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1 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action