Zfp42 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000051176 T101270_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; regulation of genetic imprinting; and spermatid development. Located in cytoplasm and nucleus. Part of protein-containing complex. Is expressed in early conceptus; gonad; tail; and ureter. Orthologous to human ZFP42 (ZFP42 zinc finger protein). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Zfp42
M09006_2.00		 Mus musculus
VGSMGCCATYTT
AARATGGCKSCB		 Misc
Kulakovskiy et al.(2013)
ZFP42_MOUSE.H11MO.0.A		 (Direct) (Direct)
Zfp42
M10351_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$REX1_01		 (Direct) (Direct)
Zfp42
M10352_2.00		 Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$REX1_02		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000080765 C2H2 ZF 170 194
ENSMUSP00000080765 C2H2 ZF 199 221
ENSMUSP00000080765 C2H2 ZF 227 251
ENSMUSP00000080765 C2H2 ZF 257 281

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

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2 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action