Zfp46 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000051351 T101273_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Is expressed in ganglia; genitourinary system; and hindbrain. Orthologous to human ZNF436 (zinc finger protein 436). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF436
M08305_2.00 		Homo sapiens
TCCTCCAGGAAGCCY
RGGCTTCCTGGAGGA		 ChIP-seq
Schmitges et al.(2016)
Q9C0F3_7-11.RCADE 		0.824 0.982
ZNF436
M08887_2.00 		Homo sapiens
CCTCCTCCAGGAAGCCYTCCHKGA
TCMDGGARGGCTTCCTGGAGGAGG		 Misc
Kulakovskiy et al.(2013)
ZN436_HUMAN.H11MO.0.C 		0.824 0.982
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000070216 C2H2 ZF 120 142
ENSMUSP00000070216 C2H2 ZF 148 170
ENSMUSP00000070216 C2H2 ZF 176 198
ENSMUSP00000070216 C2H2 ZF 204 226
ENSMUSP00000070216 C2H2 ZF 232 254
ENSMUSP00000070216 C2H2 ZF 260 282
ENSMUSP00000070216 C2H2 ZF 288 310
ENSMUSP00000070216 C2H2 ZF 316 338
ENSMUSP00000070216 C2H2 ZF 344 366
ENSMUSP00000070216 C2H2 ZF 372 394
ENSMUSP00000070216 C2H2 ZF 400 422
ENSMUSP00000070216 C2H2 ZF 428 450
ENSMUSP00000118495 C2H2 ZF 120 142

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

40 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Zfp46 Rattus norvegicus ENSRNOG00000049975 I 0.825
ENSOARG00000007586 Ovis aries ENSOARG00000007586 I 0.824
ZNF436 Ochotona princeps ENSOPRG00000012417 I 0.824
ZNF436 Otolemur garnettii ENSOGAG00000009181 I 0.824
ENSNLEG00000008477 Nomascus leucogenys ENSNLEG00000008477 I 0.824
ENSAMEG00000009576 Ailuropoda melanoleuca ENSAMEG00000009576 I 0.824
ENSMPUG00000015896 Mustela putorius furo ENSMPUG00000015896 I 0.824
ENSPANG00000018160 Papio anubis ENSPANG00000018160 I 0.824
ENSPPYG00000001743 Pongo abelii ENSPPYG00000001743 I 0.824
ENSSSCG00000023614 Sus scrofa ENSSSCG00000023614 I 0.824
ZNF436 Tupaia belangeri ENSTBEG00000002827 I 0.824
ZNF436 Sorex araneus ENSSARG00000012155 I 0.824
ZNF436 Pteropus vampyrus ENSPVAG00000014803 I 0.824
ENSP00000324064-D75 Bos grunniens ENSP00000324064-D75 I 0.824
ZNF436 Pan troglodytes ENSPTRG00000000325 I 0.824
ZNF436 Procavia capensis ENSPCAG00000010535 I 0.824
ZNF436 Macaca mulatta ENSMMUG00000010973 I 0.824
ENSCSAG00000000923 Chlorocebus sabaeus ENSCSAG00000000923 I 0.824
ZNF436 Dasypus novemcinctus ENSDNOG00000015883 I 0.824
ZNF436 Equus caballus ENSECAG00000011988 I 0.824
ZNF436 Callithrix jacchus ENSCJAG00000005489 I 0.824
ZNF436 Choloepus hoffmanni ENSCHOG00000005098 I 0.824
ZNF436 Bos taurus ENSBTAG00000002594 I 0.824
ZNF436 Canis familiaris ENSCAFG00000031798 I 0.824
ZNF436 Erinaceus europaeus ENSEEUG00000005276 I 0.824
Zfp46 Dipodomys ordii ENSDORG00000007438 I 0.824
ZNF436 Loxodonta africana ENSLAFG00000012795 I 0.824
Myotis_brandtii_ZNF436_10029737 Myotis brandtii Myotis_brandtii_ZNF436_10029737 I 0.824
ZNF436 Microcebus murinus ENSMICG00000005876 I 0.824
ZNF436 Felis catus ENSFCAG00000030008 I 0.824
ZNF436 Gorilla gorilla ENSGGOG00000011273 I 0.824
ZNF436 Homo sapiens ENSG00000125945 D 0.824
ENSCPOG00000011396 Cavia porcellus ENSCPOG00000011396 I 0.823
ENSSTOG00000001212 Ictidomys tridecemlineatus ENSSTOG00000001212 I 0.823
ZNF436 Vicugna pacos ENSVPAG00000006412 I 0.822
ZNF436 Tursiops truncatus ENSTTRG00000007756 I 0.822
ZNF436 Myotis lucifugus ENSMLUG00000007596 I 0.821
ZNF436 Oryctolagus cuniculus ENSOCUG00000010670 I 0.818
ZNF436 Monodelphis domestica ENSMODG00000016145 I 0.807
ENSMEUG00000013368 Macropus eugenii ENSMEUG00000013368 I 0.807