Zfp580 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000055633 T101317_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cellular response to hydrogen peroxide; positive regulation of cell migration; and regulation of gene expression. Predicted to act upstream of or within chemotaxis and inflammatory response. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including aorta; endocrine gland; genitourinary system; nervous system; and trachea. Orthologous to human ZNF580 (zinc finger protein 580). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZNF580
M04637_2.00 		Homo sapiens
VCTACCCYHNVCTACCCY
RGGGTAGBNDRGGGTAGB		 SELEX
Yin et al.(2017)
ZNF580_eDBD_HT-SELEX 		0.827 1.000
ZNF580
M04639_2.00 		Homo sapiens
VCTACCNYHNNVCTACCNH
DNGGTAGBNNDRNGGTAGB		 SELEX
Yin et al.(2017)
ZNF580_FL_HT-SELEX_1 		0.827 1.000
ZNF580
M04640_2.00 		Homo sapiens
BRTTATGTTAAATWRTTACCNYN
NRNGGTAAYWATTTAACATAAYV		 SELEX
Yin et al.(2017)
ZNF580_FL_HT-SELEX_2 		0.827 1.000
ZNF580
M04638_2.00 		Homo sapiens
MCTACCCTHRMCTACCCT
AGGGTAGKYDAGGGTAGK		 SELEX
Yin et al.(2017)
ZNF580_eDBD_Methyl-HT-SELEX 		0.827 1.000
ZNF580
M04641_2.00 		Homo sapiens
MCTACCHYNNNMCTACCHH
DDGGTAGKNNNRDGGTAGK		 SELEX
Yin et al.(2017)
ZNF580_FL_Methyl-HT-SELEX_1 		0.827 1.000
ZNF580
M04642_2.00 		Homo sapiens
NRTTATGTTAAATWRTTACCHTN
NADGGTAAYWATTTAACATAAYN		 SELEX
Yin et al.(2017)
ZNF580_FL_Methyl-HT-SELEX_2 		0.827 1.000
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000065861 C2H2 ZF 92 114
ENSMUSP00000065861 C2H2 ZF 120 142
ENSMUSP00000065861 C2H2 ZF 150 172

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

Invalid Input OrderBy

20 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action