EGR1 (Oryctolagus cuniculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSOCUG00000008439 T103038_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Egr1
M01864_2.00
Mus musculus
CCCMCGYNN

NNRCGKGGG
PBM
Weirauch et al.(2014)
pTH5337
0.827 1.000
Egr1
M00375_2.00
Mus musculus
NCCYMCDNN

NNHGKRGGN
PBM
Berger et al.(2006)
Zif268
0.827 1.000
EGR1
M02883_2.00
Homo sapiens
NMCGCCCMCGCANN

NNTGCGKGGGCGKN
SELEX
Jolma et al.(2013)
EGR1_1
0.827 1.000
EGR1
M02884_2.00
Homo sapiens
HMCGCCCACGCAHW

WDTGCGTGGGCGKD
SELEX
Jolma et al.(2013)
EGR1_2
0.827 1.000
Egr1
M02932_2.00
Mus musculus
HHMCGCCCMCBCAHHH

DDDTGVGKGGGCGKDD
SELEX
Jolma et al.(2013)
Egr1_1
0.827 1.000
EGR1
M04437_2.00
Homo sapiens
NNCRCCCMCRCNN

NNGYGKGGGYGNN
SELEX
Yin et al.(2017)
EGR1_eDBD_HT-SELEX
0.827 1.000
Egr1
M05860_2.00
Mus musculus
NNMCRCCCMCGCN

NGCGKGGGYGKNN
SMiLE-seq
Isakova et al.(2017)
EGR1
0.827 1.000
EGR1
M07927_2.00
Homo sapiens
NVBNNNNBCCGCCCMCGCNB

VNGCGKGGGCGGVNNNNVBN
ChIP-seq
Gerstein et al.(2012)
GM12878_EGR1_HudsonAlpha
0.827 1.000
EGR1
M07928_2.00
Homo sapiens
BNCCGCCCMCGCNBB

VVNGCGKGGGCGGNV
ChIP-seq
Gerstein et al.(2012)
H1-hESC_EGR1_HudsonAlpha
0.827 1.000
EGR1
M07929_2.00
Homo sapiens
NNNNNNBNNCCRCCCMCGCN

NGCGKGGGYGGNNVNNNNNN
ChIP-seq
Gerstein et al.(2012)
K562_EGR1_HudsonAlpha
0.827 1.000
EGR1
M08882_2.00
Homo sapiens
BHNCCDCCCMCDCHBNB

VNVDGHGKGGGHGGNDV
Misc
Kulakovskiy et al.(2013)
EGR1_HUMAN.H11MO.0.A
0.827 1.000
Egr1
M08996_2.00
Mus musculus
YYCCRCCCMCGCNB

VNGCGKGGGYGGRR
Misc
Kulakovskiy et al.(2013)
EGR1_MOUSE.H11MO.0.A
0.827 1.000
EGR1
M09506_2.00
Homo sapiens
CRCCCMCRCA

TGYGKGGGYG
Misc
Heinz et al.(2010)
K562-Egr1_GSE32465
0.827 1.000
EGR1
M10188_2.00
Homo sapiens
MCGCCYACGCAW

WTGCGTRGGCGK
Transfac
Matys et al.(2006)
V$EGR1_01
0.827 1.000
EGR1
M10189_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR1_02
0.827 1.000
EGR1
M10190_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR1_09
0.827 1.000
EGR1
M10191_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR1_11
0.827 1.000
EGR1
M10192_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR1_12
0.827 1.000
EGR1
M10193_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR1_13
0.827 1.000
EGR1
M10194_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR1_15
0.827 1.000
EGR1
M10195_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR1_Q3
0.827 1.000
EGR1
M10196_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR1_Q6
0.827 1.000
EGR1
M04438_2.00
Homo sapiens
NHCDCCCMCNYNN

NNRNGKGGGHGDN
SELEX
Yin et al.(2017)
EGR1_eDBD_Methyl-HT-SELEX
0.827 1.000
Egr3
M00776_2.00
Mus musculus
HHDCCCMCDN

NHGKGGGHDD
PBM
Weirauch et al.(2013)
pTH2820
0.816 0.899
EGR3
M02915_2.00
Homo sapiens
NHMCGCCCMCGCAHN

NDTGCGKGGGCGKDN
SELEX
Jolma et al.(2013)
EGR3_1
0.816 0.899
Egr3
M02931_2.00
Mus musculus
HMCGCCCACGCAHWN

NWDTGCGTGGGCGKD
SELEX
Jolma et al.(2013)
Egr3_1
0.816 0.899
EGR3
M04583_2.00
Homo sapiens
HMCGCCCACGCRH

DYGCGTGGGCGKD
SELEX
Yin et al.(2017)
EGR3_FL_HT-SELEX
0.816 0.899
EGR3
M08349_2.00
Homo sapiens
CDCCYCCDC

GHGGRGGHG
ChIP-seq
Schmitges et al.(2016)
Q06889_1-3.RCADE
0.816 0.899
EGR3
M10279_2.00
Homo sapiens
MCGCCYACGCWN

NWGCGTRGGCGK
Transfac
Matys et al.(2006)
V$EGR3_01
0.816 0.899
EGR3
M10280_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR3_Q3
0.816 0.899
EGR3
M10281_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR3_Q6
0.816 0.899
EGR3
M04584_2.00
Homo sapiens
NMCGCCCACGCRH

DYGCGTGGGCGKN
SELEX
Yin et al.(2017)
EGR3_FL_Methyl-HT-SELEX
0.816 0.899
EGR4
M02889_2.00
Homo sapiens
NHMCGCCCACGCAHHN

NDDTGCGTGGGCGKDN
SELEX
Jolma et al.(2013)
EGR4_1
0.804 0.812
EGR4
M02890_2.00
Homo sapiens
NHMCGCCCACGCAHWH

DWDTGCGTGGGCGKDN
SELEX
Jolma et al.(2013)
EGR4_2
0.804 0.812
EGR4
M04461_2.00
Homo sapiens
HMCGCCCACGCAH

DTGCGTGGGCGKD
SELEX
Yin et al.(2017)
EGR4_eDBD_HT-SELEX
0.804 0.812
EGR4
M10216_2.00
Homo sapiens
MCRCCCACGCAW

WTGCGTGGGYGK
Transfac
Matys et al.(2006)
V$NGFIC_01
0.804 0.812
EGR4
M04462_2.00
Homo sapiens
HMCGCCCMCGCRH

DYGCGKGGGCGKD
SELEX
Yin et al.(2017)
EGR4_eDBD_Methyl-HT-SELEX
0.804 0.812
EGR2
M00233_2.00
Homo sapiens
HDCCCMCDBN

NVHGKGGGHD
PBM
Barrera et al.(2016)
EGR2_REF
0.803 0.957
Egr2
M00778_2.00
Mus musculus
YRCCCMCGYN

NRCGKGGGYR
PBM
Weirauch et al.(2013)
pTH3091
0.803 0.957
EGR2
M02885_2.00
Homo sapiens
MCGCCCACGCD

HGCGTGGGCGK
SELEX
Jolma et al.(2013)
EGR2_1
0.803 0.957
EGR2
M02886_2.00
Homo sapiens
NNMCGCCCACGCDNN

NNHGCGTGGGCGKNN
SELEX
Jolma et al.(2013)
EGR2_2
0.803 0.957
EGR2
M04439_2.00
Homo sapiens
HMCRCCCACGCNN

NNGCGTGGGYGKD
SELEX
Yin et al.(2017)
EGR2_FL_HT-SELEX
0.803 0.957
EGR2
M08302_2.00
Homo sapiens
CDCCCMCDC

GHGKGGGHG
ChIP-seq
Schmitges et al.(2016)
P11161_1-3.RCADE
0.803 0.957
EGR2
M08884_2.00
Homo sapiens
YYCCDCCCMCDCHYHYHY

RDRDRDGHGKGGGHGGRR
Misc
Kulakovskiy et al.(2013)
EGR2_HUMAN.H11MO.0.A
0.803 0.957
Egr2
M08994_2.00
Mus musculus
BHYCCDCCCMCDCN

NGHGKGGGHGGRDV
Misc
Kulakovskiy et al.(2013)
EGR2_MOUSE.H11MO.0.A
0.803 0.957
Egr2
M09515_2.00
Mus musculus
NMCRCCCACDSN

NSHGTGGGYGKN
Misc
Heinz et al.(2010)
Thymocytes-Egr2_GSE34254
0.803 0.957
EGR2
M10197_2.00
Homo sapiens
MCGCCYACGCAH

DTGCGTRGGCGK
Transfac
Matys et al.(2006)
V$EGR2_01
0.803 0.957
EGR2
M10198_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR2_Q4
0.803 0.957
EGR2
M10199_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EGR2_Q6
0.803 0.957
EGR2
M04440_2.00
Homo sapiens
NMCGCCCACRCRN

NYGYGTGGGCGKN
SELEX
Yin et al.(2017)
EGR2_FL_Methyl-HT-SELEX
0.803 0.957
EGR2
M00232_2.00
Homo sapiens
NHMCGCCYNN

NNRGGCGKDN
PBM
Barrera et al.(2016)
EGR2_R409W
0.802 0.942
sr
M06072_2.00
Drosophila melanogaster
HVMCGCCCMCVYMH

DKRBGKGGGCGKBD
B1H
Zhu et al.(2011)
sr_SANGER_5_FBgn0003499
0.801 0.913
sr
M06073_2.00
Drosophila melanogaster
NNMCRCCCMCVHNN

NNDBGKGGGYGKNN
B1H
Zhu et al.(2011)
sr_SOLEXA_5_FBgn0003499
0.801 0.913
egrh-1
M00622_2.00
Caenorhabditis elegans
CSCCCMCR

YGKGGGSG
PBM
Narasimhan et al.(2015)
pTH9317
0.785 0.899
EGR2
M00231_2.00
Homo sapiens
MCCMCGCD

HGCGKGGK
PBM
Barrera et al.(2016)
EGR2_R359W
0.757 0.942
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSOCUP00000007289 C2H2 ZF 337 361
ENSOCUP00000007289 C2H2 ZF 367 389
ENSOCUP00000007289 C2H2 ZF 395 417
ENSOCUP00000022775 C2H2 ZF 303 327
ENSOCUP00000022775 C2H2 ZF 333 355
ENSOCUP00000022775 C2H2 ZF 361 383

Links

Other C2H2 ZF family TFs
Other Oryctolagus cuniculus TFs

371 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ATEG_08244 Aspergillus terreus CADATEAG00003887 N 0.000
CADAFLAG00012297 Aspergillus flavus CADAFLAG00012297 I 0.000
CADAORAG00004258 Aspergillus oryzae CADAORAG00004258 I 0.000
CFIO01_03805 Colletotrichum fioriniae CFIO01_03805 I 0.000
CGGC5_3013 Colletotrichum gloeosporioides CGGC5_3013 I 0.000
Cob_02984 Colletotrichum orbiculare Cob_02984 I 0.000
CSUB01_02738 Colletotrichum sublineola CSUB01_02738 I 0.000
DOTSEDRAFT_71818 Dothistroma septosporum DOTSEDRAFT_71818 N 0.000
estExt_Genewise1Plus.C_chr_50835 Mycosphaerella graminicola estExt_Genewise1Plus.C_chr_50835 N 0.000
F503_01249 Ophiostoma piceae uamh F503_01249 I 0.000
FFUJ_09498 Fusarium fujikuroi FFUJ_09498 N 0.000
FGRRES_16159 Fusarium graminearum FGRRES_16159 N 0.000
FOXG_11581 Fusarium oxysporum FOXG_11581 N 0.000
FPSE_05211 Fusarium pseudograminearum FPSE_05211 N 0.000
FVEG_10243 Fusarium verticillioides FVEG_10243 N 0.000
GLRG_09907 Colletotrichum graminicola GLRG_09907 I 0.000
gw1.11.59.1 Mycosphaerella fijiensis gw1.11.59.1 N 0.000
MAC_02441 Metarhizium acridum MAC_02441 I 0.000
MAJ_10813 Metarhizium majus MAJ_10813 I 0.000
MANI_013399 Metarhizium anisopliae MANI_013399 N 0.000
MBM_00253 Marssonina brunnea MBM_00253 I 0.000
MBR_05903 Metarhizium brunneum MBR_05903 N 0.000
MGU_06573 Metarhizium guizhouense MGU_06573 N 0.000
MPH_01921 Macrophomina phaseolina MPH_01921 I 0.000
MYCFIDRAFT_142135 Pseudocercospora fijiensis MYCFIDRAFT_142135 N 0.000
Mycgr3G72224 Zymoseptoria tritici Mycgr3G72224 N 0.000
OIDMADRAFT_149569 Oidiodendron maius OIDMADRAFT_149569 N 0.000
OIDMADRAFT_160412 Oidiodendron maius OIDMADRAFT_160412 N 0.000
PABG_05542 Paracoccidioides brasiliensis PABG_05542 N 0.000
Pc12g02800 Penicillium chrysogenum Pc12g02800 N 0.000
PCH_Pc12g02800 Penicillium rubens PCH_Pc12g02800 N 0.000
PDE_06431 Penicillium oxalicum PDE_06431 N 0.000
PEX1_064660 Penicillium expansum PEX1_064660 N 0.000
PV05_03582 Exophiala xenobiotica PV05_03582 I 0.000
SEPMUDRAFT_157964 Sphaerulina musiva SEPMUDRAFT_157964 N 0.000
VDAG_00765 Verticillium dahliae VDAG_00765 I 0.000
VDBG_01161 Verticillium alfalfae VDBG_01161 I 0.000
VDBG_01161 Verticillium albo atrum VDBG_01161 I 0.000
X797_005648 Metarhizium robertsii X797_005648 N 0.000