Zbtb49 (Rattus norvegicus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSRNOG00000005633 T108905_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coactivator binding activity. Predicted to be involved in negative regulation of cell population proliferation; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle. Predicted to be located in cytosol; microtubule cytoskeleton; and nucleus. Predicted to be active in nucleoplasm. Orthologous to human ZBTB49 (zinc finger and BTB domain containing 49). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ZBTB49
M02901_2.00 		Homo sapiens
TTYYGCYTGRCVBGTCA
TGACVBGYCARGCRRAA		 SELEX
Jolma et al.(2013)
ZBTB49_1 		0.811 0.963
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000042665 C2H2 ZF 388 410
ENSRNOP00000068611 C2H2 ZF 388 410
ENSRNOP00000068611 C2H2 ZF 416 438
ENSRNOP00000068611 C2H2 ZF 444 466
ENSRNOP00000068611 C2H2 ZF 472 494
ENSRNOP00000068611 C2H2 ZF 500 522
ENSRNOP00000068611 C2H2 ZF 528 550
ENSRNOP00000068611 C2H2 ZF 556 578

Links

Other C2H2 ZF family TFs
Other Rattus norvegicus TFs

49 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ZBTB49 Macaca mulatta ENSMMUG00000023394 I 0.827
ENSTBEG00000002526 Tupaia belangeri ENSTBEG00000002526 N 0.827
ZBTB49 Homo sapiens ENSG00000168826 D 0.827
Zbtb49 Mus musculus ENSMUSG00000029127 I 0.827
ZBTB49 Cavia porcellus ENSCPOG00000007981 I 0.817
ENSTBEG00000005000 Tupaia belangeri ENSTBEG00000005000 I 0.814
ZBTB49 Pteropus vampyrus ENSPVAG00000015185 I 0.814
ENSSTOG00000000550 Ictidomys tridecemlineatus ENSSTOG00000000550 I 0.814
ZBTB49 Oryctolagus cuniculus ENSOCUG00000007993 I 0.814
ENSFALG00000009426 Ficedula albicollis ENSFALG00000009426 I 0.813
ZBTB49 Otolemur garnettii ENSOGAG00000000988 I 0.811
ZBTB49 Callithrix jacchus ENSCJAG00000000119 I 0.811
ENSPANG00000015665 Papio anubis ENSPANG00000015665 I 0.811
ENSCSAG00000016270 Chlorocebus sabaeus ENSCSAG00000016270 I 0.811
ZBTB49 Pan troglodytes ENSPTRG00000015868 I 0.811
ZBTB49 Gorilla gorilla ENSGGOG00000013012 I 0.811
ZBTB49 Dasypus novemcinctus ENSDNOG00000016261 I 0.811
ZBTB49 Equus caballus ENSECAG00000013694 I 0.811
ENSPPYG00000014601 Pongo abelii ENSPPYG00000014601 I 0.811
ENSNLEG00000016142 Nomascus leucogenys ENSNLEG00000016142 I 0.811
ENSMICG00000000204 Microcebus murinus ENSMICG00000000204 I 0.810
ZBTB49 Loxodonta africana ENSLAFG00000016590 I 0.808
ZBTB49 Bos taurus ENSBTAG00000014680 I 0.806
ENSP00000338807-D1 Bos grunniens ENSP00000338807-D1 I 0.806
ZBTB49 Canis familiaris ENSCAFG00000015688 I 0.805
ZBTB49 Sus scrofa ENSSSCG00000008728 I 0.805
ENSOARG00000007577 Ovis aries ENSOARG00000007577 I 0.804
Gfo_R014333 Geospiza fortis Gfo_R014333 I 0.803
ENSPSIG00000015554 Pelodiscus sinensis ENSPSIG00000015554 I 0.803
ZBTB49 Taeniopygia guttata ENSTGUG00000009920 I 0.803
ZBTB49 Gallus gallus ENSGALG00000015009 I 0.803
Aan_R008590 Calypte anna Aan_R008590 I 0.803
Afo_R000623 Aptenodytes forsteri Afo_R000623 I 0.803
ZBTB49 Meleagris gallopavo ENSMGAG00000012706 I 0.803
ENSAPLG00000003489 Anas platyrhynchos ENSAPLG00000003489 I 0.803
ENSAMEG00000013670 Ailuropoda melanoleuca ENSAMEG00000013670 I 0.803
ENSLACG00000007886 Latimeria chalumnae ENSLACG00000007886 I 0.802
Brh_R008967 Buceros rhinoceros Brh_R008967 I 0.798
Myotis_brandtii_ZBTB49_10013405 Myotis brandtii Myotis_brandtii_ZBTB49_10013405 I 0.793
ZBTB49 Myotis lucifugus ENSMLUG00000009904 I 0.793
ZBTB49 Felis catus ENSFCAG00000015510 I 0.790
ZBTB49 Anolis carolinensis ENSACAG00000010957 I 0.785
ENSMPUG00000007961 Mustela putorius furo ENSMPUG00000007961 N 0.779
Pvit_18935 Pogona vitticeps Pvit_18935 I 0.770
ENSOANG00000010145 Ornithorhynchus anatinus ENSOANG00000010145 N 0.769
ENSSHAG00000008414 Sarcophilus harrisii ENSSHAG00000008414 I 0.769
ZBTB49 Monodelphis domestica ENSMODG00000001516 I 0.768
ENSLOCG00000009974 Lepisosteus oculatus ENSLOCG00000009974 I 0.766
zbtb49 Xenopus tropicalis XB-GENE-992553 N 0.757