Sall4 (Rattus norvegicus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSRNOG00000050035 T109297_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including chordate embryonic development; embryonic limb morphogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in heterochromatin and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Duane retraction syndrome; Duane-radial ray syndrome; Holt-Oram syndrome; IVIC syndrome; and ventricular septal defect. Orthologous to human SALL4 (spalt like transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SALL4
M08866_2.00 		Homo sapiens
CMCWCCCHNN
NNDGGGWGKG		 Misc
Kulakovskiy et al.(2013)
SALL4_HUMAN.H11MO.0.B 		0.816 0.957
Sall4
M08979_2.00 		Mus musculus
CMCWCCCHNN
NNDGGGWGKG		 Misc
Kulakovskiy et al.(2013)
SALL4_MOUSE.H11MO.0.A 		0.814 0.957
Sall4
M10341_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$DRRS_05 		0.814 0.957
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000066945 C2H2 ZF 91 113
ENSRNOP00000066945 C2H2 ZF 119 141
ENSRNOP00000067726 C2H2 ZF 385 407
ENSRNOP00000067726 C2H2 ZF 413 435
ENSRNOP00000067726 C2H2 ZF 600 622
ENSRNOP00000067726 C2H2 ZF 632 654
ENSRNOP00000067726 C2H2 ZF 879 901
ENSRNOP00000067726 C2H2 ZF 907 929

Links

Other C2H2 ZF family TFs
Other Rattus norvegicus TFs

34 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
SALL4 Microcebus murinus ENSMICG00000000027 I 0.816
SALL4 Gorilla gorilla ENSGGOG00000001832 I 0.816
SALL4 Homo sapiens ENSG00000101115 D 0.816
ENSNLEG00000007013 Nomascus leucogenys ENSNLEG00000007013 I 0.816
ENSPANG00000021792 Papio anubis ENSPANG00000021792 I 0.816
SALL4 Tursiops truncatus ENSTTRG00000007753 I 0.816
SALL4 Pan troglodytes ENSPTRG00000013631 I 0.816
SALL4 Erinaceus europaeus ENSEEUG00000003649 I 0.816
SALL4 Macaca mulatta ENSMMUG00000003870 I 0.816
ENSCJAG00000000591 Callithrix jacchus ENSCJAG00000000591 I 0.816
SALL4 Dasypus novemcinctus ENSDNOG00000040633 I 0.816
ENSCSAG00000015269 Chlorocebus sabaeus ENSCSAG00000015269 I 0.816
Sall4 Mus musculus ENSMUSG00000027547 D 0.814
ENSSTOG00000025002 Ictidomys tridecemlineatus ENSSTOG00000025002 I 0.814
SALL4 Pteropus vampyrus ENSPVAG00000002075 I 0.808
ENSP00000217086 Macaca fascicularis ENSP00000217086 I 0.806
SALL4 Loxodonta africana ENSLAFG00000004309 I 0.806
ENSCJAG00000021107 Callithrix jacchus ENSCJAG00000021107 N 0.803
ENSMLUG00000007060 Myotis lucifugus ENSMLUG00000007060 I 0.803
SALL4 Equus caballus ENSECAG00000018533 N 0.803
SALL4 Sus scrofa ENSSSCG00000007479 I 0.797
ENSTSYG00000007359 Tarsius syrichta ENSTSYG00000007359 I 0.784
ENSPPYG00000011138 Pongo abelii ENSPPYG00000011138 I 0.779
ENSCAFG00000011738 Canis familiaris ENSCAFG00000011738 I 0.779
SALL4 Otolemur garnettii ENSOGAG00000013799 I 0.779
ENSAMEG00000013250 Ailuropoda melanoleuca ENSAMEG00000013250 I 0.779
SALL4 Ochotona princeps ENSOPRG00000011640 I 0.779
ENSMPUG00000017543 Mustela putorius furo ENSMPUG00000017543 I 0.779
ENSMLUG00000008405 Myotis lucifugus ENSMLUG00000008405 I 0.777
SALL4 Felis catus ENSFCAG00000002822 I 0.777
SALL4 Bos taurus ENSBTAG00000003101 I 0.769
SALL4 Oryctolagus cuniculus ENSOCUG00000011797 I 0.767
Ogr03507 Ophisaurus gracilis Ogr03507 N 0.758
ENSTGUG00000018244 Taeniopygia guttata ENSTGUG00000018244 N 0.758