CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Sall4
(
Rattus norvegicus
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSRNOG00000050035
T109297_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including chordate embryonic development; embryonic limb morphogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in heterochromatin and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Duane retraction syndrome; Duane-radial ray syndrome; Holt-Oram syndrome; IVIC syndrome; and ventricular septal defect. Orthologous to human SALL4 (spalt like transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
SALL4
M08866_2.00
Homo sapiens
CMCWCCCHNN
NNDGGGWGKG
Misc
Kulakovskiy et al.(2013)
SALL4_HUMAN.H11MO.0.B
0.816
0.957
Sall4
M08979_2.00
Mus musculus
CMCWCCCHNN
NNDGGGWGKG
Misc
Kulakovskiy et al.(2013)
SALL4_MOUSE.H11MO.0.A
0.814
0.957
Sall4
M10341_2.00
Mus musculus
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$DRRS_05
0.814
0.957
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000066945
C2H2 ZF
91
113
HSCTRCGKNFSSASALQIHERTH
ENSRNOP00000066945
C2H2 ZF
119
141
FVCNICARAFTTKGNLKVHYMTH
ENSRNOP00000067726
C2H2 ZF
385
407
HKCRYCSKVFGTDSSLQIHLRSH
ENSRNOP00000067726
C2H2 ZF
413
435
YVCPVCGHRFTTKGNLKVHFHRH
ENSRNOP00000067726
C2H2 ZF
600
622
FQCKICGRAFSTKGNLKTHLGVH
ENSRNOP00000067726
C2H2 ZF
632
654
HSCPICQKKFTNAVMLQQHIRMH
ENSRNOP00000067726
C2H2 ZF
879
901
HSCTRCGKNFSSASALQIHERTH
ENSRNOP00000067726
C2H2 ZF
907
929
FVCNICARAFTTKGNLKVHYMTH
Links
Other
C2H2 ZF
family TFs
Other
Rattus norvegicus
TFs
34 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy