Hic2 (Rattus norvegicus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSRNOG00000051458 T109308_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein C-terminus binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Orthologous to human HIC2 (HIC ZBTB transcriptional repressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
HIC2
M02902_2.00
Homo sapiens
RTGCCMVNN

NNBKGGCAY
SELEX
Jolma et al.(2013)
HIC2_1
0.827 1.000
Hic1
M00141_2.00
Mus musculus
RTGCCMNBN

NVNKGGCAY
PBM
Badis et al.(2009)
Hic1_2816
0.795 0.852
Hic1
M02933_2.00
Mus musculus
RTGCCAVCYBRTGCCAVC

GBTGGCAYVRGBTGGCAY
SELEX
Jolma et al.(2013)
Hic1_1
0.795 0.852
Hic1
M02934_2.00
Mus musculus
RTGCCAVCN

NGBTGGCAY
SELEX
Jolma et al.(2013)
Hic1_2
0.795 0.852
Hic1
M09003_2.00
Mus musculus
KGGCAMCCH

DGGKTGCCM
Misc
Kulakovskiy et al.(2013)
HIC1_MOUSE.H11MO.0.C
0.795 0.852
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000072722 C2H2 ZF 448 470
ENSRNOP00000072722 C2H2 ZF 512 534
ENSRNOP00000072722 C2H2 ZF 540 562
ENSRNOP00000072722 C2H2 ZF 568 590
ENSRNOP00000072722 C2H2 ZF 596 618

Links

Other C2H2 ZF family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

64 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action