Klf11 (Rattus norvegicus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSRNOG00000054259 T109329_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to peptide. Predicted to be located in cytosol; focal adhesion; and nuclear body. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 7 and type 2 diabetes mellitus. Orthologous to human KLF11 (Kruppel like factor 11). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
KLF11
M00242_2.00 		Homo sapiens
MCGCCCCC
GGGGGCGK		 PBM
Barrera et al.(2016)
KLF11_REF 		0.808 0.971
KLF11
M04554_2.00 		Homo sapiens
VMCMCRCCCMYNMCACGCCCMC
GKGGGCGTGKNRKGGGYGKGKB		 SELEX
Yin et al.(2017)
KLF11_eDBD_HT-SELEX 		0.808 0.971
KLF11
M10261_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FKLF_Q5 		0.808 0.971
KLF11
M00241_2.00 		Homo sapiens
MCGCCCMC
GKGGGCGK		 PBM
Barrera et al.(2016)
KLF11_R402Q 		0.808 0.971
KLF11
M04555_2.00 		Homo sapiens
VMCMCRCCCHYNHCACGCCCMC
GKGGGCGTGDNRDGGGYGKGKB		 SELEX
Yin et al.(2017)
KLF11_eDBD_Methyl-HT-SELEX 		0.808 0.971
KLF10
M04489_2.00 		Homo sapiens
RMCACRCCCMYVHCACRCCCMC
GKGGGYGTGDBRKGGGYGTGKY		 SELEX
Yin et al.(2017)
KLF10_eDBD_HT-SELEX 		0.771 0.841
KLF10
M08246_2.00 		Homo sapiens
RCCMCRCCCH
DGGGYGKGGY		 ChIP-seq
Najafabadi et al.(2015b)
KLF10 		0.771 0.841
KLF10
M08317_2.00 		Homo sapiens
SMCMCRCCCMYNBSN
NSVNRKGGGYGKGKS		 ChIP-seq
Schmitges et al.(2016)
Q13118.MEME 		0.771 0.841
KLF10
M10228_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TIEG1_Q6 		0.771 0.841
KLF10
M04490_2.00 		Homo sapiens
RMCACRCCCMYGMCACRCCCHC
GDGGGYGTGKCRKGGGYGTGKY		 SELEX
Yin et al.(2017)
KLF10_eDBD_Methyl-HT-SELEX 		0.771 0.841
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000075389 C2H2 ZF 383 407
ENSRNOP00000075389 C2H2 ZF 413 437
ENSRNOP00000075389 C2H2 ZF 443 465

Links

Other C2H2 ZF family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

156 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action