| NCBI Gene Info:Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in axon guidance and positive regulation of neuron differentiation. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; extended germ band embryo; eye disc; sensory nervous system primordium; and somatic precursor cell. Used to study brain cancer. Orthologous to human INSM1 (INSM transcriptional repressor 1) and INSM2 (INSM transcriptional repressor 2). [provided by Alliance of Genome Resources, Apr 2022] |