CG9650 (Drosophila melanogaster)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 FBgn0029939 T114468_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of peptide hormone secretion. Located in cytosol. Is expressed in several structures, including dorsal sensory complex proper primordium; extended germ band embryo; foregut primordium; presumptive embryonic/larval system; and visceral muscle primordium. Used to study neurodegenerative disease and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; immunodeficiency 49; schizophrenia; and sickle cell anemia. Orthologous to several human genes including BCL11A (BAF chromatin remodeling complex subunit BCL11A) and BCL11B (BAF chromatin remodeling complex subunit BCL11B). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0290458 C2H2 ZF 713 735
FBpp0290458 C2H2 ZF 741 763
FBpp0290458 C2H2 ZF 1024 1046
FBpp0290458 C2H2 ZF 1052 1074
FBpp0290458 C2H2 ZF 1082 1103
FBpp0290459 C2H2 ZF 713 735
FBpp0290459 C2H2 ZF 741 763
FBpp0290459 C2H2 ZF 1024 1046
FBpp0290459 C2H2 ZF 1052 1074
FBpp0290459 C2H2 ZF 1082 1103
FBpp0301059 C2H2 ZF 711 733
FBpp0301059 C2H2 ZF 739 761
FBpp0301059 C2H2 ZF 1022 1044
FBpp0301059 C2H2 ZF 1050 1072
FBpp0301059 C2H2 ZF 1080 1101
FBpp0308848 C2H2 ZF 644 666
FBpp0308848 C2H2 ZF 672 694
FBpp0308848 C2H2 ZF 955 977
FBpp0308848 C2H2 ZF 983 1005
FBpp0308848 C2H2 ZF 1013 1034

Links

Other C2H2 ZF family TFs
Other Drosophila melanogaster TFs

12 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
GM17509 Drosophila sechellia FBgn0172417 N 0.827
GE15704 Drosophila yakuba FBgn0233271 N 0.827
GG19635 Drosophila erecta FBgn0111837 N 0.827
GD16837 Drosophila simulans FBgn0068669 N 0.827
GA23719 Drosophila pseudoobscura FBgn0245118 N 0.818
GK16386 Drosophila willistoni FBgn0218388 N 0.818
GL14690 Drosophila persimilis FBgn0152294 N 0.818
GI15941 Drosophila mojavensis FBgn0138690 N 0.816
GF21345 Drosophila ananassae FBgn0098347 N 0.816
LCUP015668 Lucilia cuprina LCUP015668 N 0.804
MDOA006732 Musca domestica MDOA006732 N 0.774