CG7368 (Drosophila melanogaster)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 FBgn0036179 T114531_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 27; gingival fibromatosis 5; and nephroblastoma. Orthologous to human REST (RE1 silencing transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CG7368
M06146_2.00		 Drosophila melanogaster
ABWWWCCCCCCCCMCYCCHM
KDGGRGKGGGGGGGGAWWVT		 B1H
Zhu et al.(2011)
CG7368_SANGER_5_FBgn0036179		 (Direct) (Direct)
CG7368
M06147_2.00		 Drosophila melanogaster
HHCCCCCHCCCMCHM
KDGKGGGDGGGGGDD		 B1H
Zhu et al.(2011)
CG7368_SOLEXA_2.5_FBgn0036179		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0110184 C2H2 ZF 328 350
FBpp0110184 C2H2 ZF 356 378
FBpp0110184 C2H2 ZF 384 406
FBpp0110184 C2H2 ZF 412 434
FBpp0297950 C2H2 ZF 328 350
FBpp0297950 C2H2 ZF 356 378
FBpp0297950 C2H2 ZF 384 406
FBpp0297950 C2H2 ZF 412 434

Links

Other C2H2 ZF family TFs
Other Drosophila melanogaster TFs

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14 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action