che-1 (Caenorhabditis elegans)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 WBGene00000483 T131550_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including response to lithium ion; response to magnesium ion; and response to methionine. Predicted to be active in nucleus. Is expressed in ASEL and ASER. Orthologous to human ZNF500 (zinc finger protein 500). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
che-1
M00609_2.00		 Caenorhabditis elegans
NGAARCCHNN
NNDGGYTTCN		 PBM
Narasimhan et al.(2015)
pTH10015		 (Direct) (Direct)
che-1
M08451_2.00		 Caenorhabditis elegans
SGYTTC
GAARCS		 COMPILED
Mathelier et al.(2014)
MA0260.1		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00609_2.00 C2H2 ZF 51 73
M00609_2.00 C2H2 ZF 79 101
M00609_2.00 C2H2 ZF 107 129
M00609_2.00 C2H2 ZF 135 157

DNA Binding Domains

Protein ID Domain From To Sequence
C55B7.12a C2H2 ZF 107 129
C55B7.12a C2H2 ZF 135 157
C55B7.12a C2H2 ZF 163 185
C55B7.12a C2H2 ZF 191 213
C55B7.12b C2H2 ZF 166 188
C55B7.12b C2H2 ZF 194 216
C55B7.12b C2H2 ZF 222 244
C55B7.12b C2H2 ZF 250 272

Links

Other C2H2 ZF family TFs
Other Caenorhabditis elegans TFs

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11 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action