BRE1 (Saccharomyces cerevisiae)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 YDL074C T131826_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA replication origin binding activity and ubiquitin protein ligase activity. Involved in several processes, including mitotic DNA damage checkpoint signaling; nucleic acid metabolic process; and protein ubiquitination. Colocalizes with chromatin. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human RNF20 (ring finger protein 20) and RNF40 (ring finger protein 40). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
YDL074C C2H2 ZF 682 700

Links

Other C2H2 ZF family TFs
Other Saccharomyces cerevisiae TFs

12 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
3485_Multiple Saccharomyces paradoxus 3485_Multiple N 0.827
3838_YDL074C Saccharomyces bayanus 3838_YDL074C N 0.827
SU7_0530 Saccharomyces arboricola SU7_0530 N 0.827
SKUD_206218 Saccharomyces kudriavzevii SKUD_206218 N 0.827
YALI0_B09559g Yarrowia lipolytica YALI0_B09559g N 0.812
CAGL0D00638g Candida glabrata CAGL0D00638g N 0.788
AGOS_AER074W Ashbya gossypii AGOS_AER074W N 0.788
ZYRO0B12804g Zygosaccharomyces rouxii ZYRO0B12804g N 0.788
ZBAI_02714 Zygosaccharomyces bailii ZBAI_02714 N 0.788
Ecym_3250 Eremothecium cymbalariae Ecym_3250 N 0.788
Kpol_1055p70 Vanderwaltozyma polyspora Kpol_1055p70 N 0.788
AACERI_AaceriAER074W Saccharomycetaceae sp ashbya aceri AACERI_AaceriAER074W N 0.788