YGR067C (Saccharomyces cerevisiae)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 YGR067C T131840_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
YGR067C
M00029_2.00		 Saccharomyces cerevisiae
HVCCCCNC
GNGGGGBD		 PBM
Badis et al.(2008)
YGR067C_2151		 (Direct) (Direct)
YGR067C
M01534_2.00		 Saccharomyces cerevisiae
NCCCCDCNNN
NNNGHGGGGN		 PBM
Zhu et al.(2009)
Ygr067c		 (Direct) (Direct)
YGR067C
M07459_2.00		 Saccharomyces cerevisiae
NCCCCDCNNNNNNN
NNNNNNNGHGGGGN		 PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0425.1		 (Direct) (Direct)
YGR067C
M08528_2.00		 Saccharomyces cerevisiae
NCCCCDCNNNNNNN
NNNNNNNGHGGGGN		 Misc
DeBoer et al.(2011)
YGR067C_548		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00029_2.00 C2H2 ZF 7 29
M00029_2.00 C2H2 ZF 35 58
M01534_2.00 C2H2 ZF 8 30
M01534_2.00 C2H2 ZF 36 59

DNA Binding Domains

Protein ID Domain From To Sequence
YGR067C C2H2 ZF 8 30
YGR067C C2H2 ZF 36 59

Links

Other C2H2 ZF family TFs
Other Saccharomyces cerevisiae TFs

19 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
8169_YGR067C Saccharomyces paradoxus 8169_YGR067C I 0.827
8484_Multiple Saccharomyces mikatae 8484_Multiple I 0.801
HPODL_04127 Ogataea parapolymorpha HPODL_04127 I 0.789
KAFR_0G03050 Kazachstania africana KAFR_0G03050 I 0.782
KNAG_0D04190 Kazachstania naganishii KNAG_0D04190 I 0.780
SAKL0H04070g Lachancea kluyveri SAKL0H04070g I 0.778
AGOS_AFR580C Ashbya gossypii AGOS_AFR580C I 0.777
AACERI_AaceriAFR580C Saccharomycetaceae sp ashbya aceri AACERI_AaceriAFR580C I 0.777
PAS_chr3_0259 Komagataella pastoris PAS_chr3_0259 I 0.777
XP_002492475.1 Pichia pastoris XP_002492475.1 I 0.777
Ecym_2760 Eremothecium cymbalariae Ecym_2760 I 0.772
KLLA0_B07909g Kluyveromyces lactis KLLA0_B07909g I 0.772
TDEL_0E01590 Torulaspora delbrueckii TDEL_0E01590 I 0.772
KUCA_T00003077001 Kuraishia capsulata KUCA_T00003077001 I 0.771
BN7_2468 Wickerhamomyces ciferrii BN7_2468 I 0.770
Kpol_472p10 Vanderwaltozyma polyspora Kpol_472p10 I 0.770
CORT_0F03430 Candida orthopsilosis CORT_0F03430 I 0.766
SPAPADRAFT_52462 Spathaspora passalidarum SPAPADRAFT_52462 I 0.765
CAGL0K04631g Candida glabrata CAGL0K04631g I 0.760