ACE2 (Saccharomyces cerevisiae)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 YLR131C T131846_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of septum digestion after cytokinesis and regulation of transcription, DNA-templated. Located in cytosol and nucleus. Orthologous to human KLF10 (Kruppel like factor 10). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ACE2
M00033_2.00		 Saccharomyces cerevisiae
NTGCTGGBYN
NRVCCAGCAN		 PBM
Badis et al.(2008)
ACE2_2082		 (Direct) (Direct)
ACE2
M07463_2.00		 Saccharomyces cerevisiae
NGCTGGB
VCCAGCN		 PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0267.1		 (Direct) (Direct)
ACE2
M08534_2.00		 Saccharomyces cerevisiae
NGCTGGBH
DVCCAGCN		 Misc
DeBoer et al.(2011)
YLR131C_1332		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SWI5
M00020_2.00 		Saccharomyces cerevisiae
NNKGCTGGTHN
NDACCAGCMNN		 PBM
Badis et al.(2008)
SWI5_2037 		0.797 0.862
SWI5
M07450_2.00 		Saccharomyces cerevisiae
KGCTGGKH
DMCCAGCM		 PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0402.1 		0.797 0.862
SWI5
M08516_2.00 		Saccharomyces cerevisiae
KGCTGGKH
DMCCAGCM		 Misc
DeBoer et al.(2011)
YDR146C_569 		0.797 0.862
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00033_2.00 C2H2 ZF 51 75
M00033_2.00 C2H2 ZF 81 105
M00033_2.00 C2H2 ZF 112 130

DNA Binding Domains

Protein ID Domain From To Sequence
YLR131C C2H2 ZF 603 627
YLR131C C2H2 ZF 633 657
YLR131C C2H2 ZF 664 682

Links

Other C2H2 ZF family TFs
Other Saccharomyces cerevisiae TFs

16 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
14324_YLR131C Saccharomyces paradoxus 14324_YLR131C I 0.827
16206_YLR131C Saccharomyces bayanus 16206_YLR131C I 0.807
SU7_2211 Saccharomyces arboricola SU7_2211 I 0.798
3580_YDR146C Saccharomyces mikatae 3580_YDR146C I 0.797
4284_YDR146C Saccharomyces paradoxus 4284_YDR146C I 0.797
4131_Multiple Saccharomyces bayanus 4131_Multiple I 0.797
SWI5 Saccharomyces cerevisiae YDR146C D 0.797
TDEL_0F04510 Torulaspora delbrueckii TDEL_0F04510 I 0.768
KNAG_0A05170 Kazachstania naganishii KNAG_0A05170 I 0.768
KAFR_0B05740 Kazachstania africana KAFR_0B05740 I 0.765
Kpol_1036p70 Vanderwaltozyma polyspora Kpol_1036p70 I 0.765
NCAS_0B03600 Naumovozyma castellii NCAS_0B03600 I 0.761
Scas_Contig693.31 Saccharomyces castellii Scas_Contig693.31 I 0.761
NDAI_0J00990 Naumovozyma dairenensis NDAI_0J00990 I 0.761
CAGL0E01331g Candida glabrata CAGL0E01331g I 0.761
Kwal_23925 Kluyveromyces waltii Kwal_23925 I 0.758